Products 23110-15-8
CAS 23110-15-8 appears in our catalog under these names: Fumagillin, 95%, Fumagillin, Fumagillin , Fumagillin/ min. 98%, Fumagillin , 95.00%. Offered by: Combi-blocks, Creative Peptides, Chemat Brand, TRC, GLPBio. Available pack sizes: 100mg, 250mg, on request, 10mg, 1mg, 5mg, 25mg, 50mg.
Fumagillin is a meroterpenoid resulting from the formal condensation of the hydroxy group of fumagillol with the carboxylic acid group of (all-E)-deca-2,4,6,8-tetraenedioic acid. Originally isolated from the fungus Aspergillus fumigatus, it is used for the control of Nosema infection in honey bees. It has a role as an antimicrobial agent, an antiprotozoal drug, an antibacterial drug, an angiogenesis inhibitor, a methionine aminopeptidase 2 inhibitor and a fungal metabolite. It is a spiro-epoxide, an organooxygen heterocyclic antibiotic, a carboxylic ester, a dicarboxylic acid monoester, a meroterpenoid and an antibiotic antifungal drug. It is functionally related to a fumagillol and an (all-E)-deca-2,4,6,8-tetraenedioic acid.
Source: ChEBI
| Molecular formula | C26H34O7 |
|---|---|
| Molecular weight | 458.5 g/mol |
| IUPAC name | (2E,4E,6E,8E)-10-[[(3R,4S,5S,6R)-5-methoxy-4-[(2R,3R)-2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-1-oxaspiro[2.5]octan-6-yl]oxy]-10-oxodeca-2,4,6,8-tetraenoic acid |
| InChIKey | NGGMYCMLYOUNGM-CSDLUJIJSA-N |
| SMILES | CC(=CC[C@@H]1[C@@](O1)(C)[C@H]2[C@@H]([C@@H](CC[C@]23CO3)OC(=O)/C=C/C=C/C=C/C=C/C(=O)O)OC)C |
Computed by PubChem (NCBI)
Synonyms:
fumagillin, Fugillin, Fumidil, Amebacilin, Fumagilina, Fumagilline, Fumagillinum, Fumagillina, Fumidil-B, (-)-Fumagillin