cas: 67469-78-7 — see every product listed under this CAS number, including other names
GBR 12909 dihydrochloride (CAS 67469-78-7) is a chemical reagent available from Chemat. Available pack sizes: 50mg, 100mg, 250mg, 500mg. Offered by: Biosynth.
| brand | Biosynth |
|---|---|
| catalog number | FG65030-50mg |
| cas | 67469-78-7 |
| size | 50mg |
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| brand | size | price | |
|---|---|---|---|
| Biosynth | 50mg | price on request | |
| Biosynth | 100mg | price on request | |
| Biosynth | 250mg | price on request | |
| Biosynth | 500mg | price on request |
| category | Life Sciences |
|---|---|
| sub-category 1 | Ligands |
| sub-category 2 | Transporters |
| purity | No data |
| delivery time | 1-2 weeks |
Vanoxerine dihydrochloride is a hydrochloride salt that is obtained by reaction of vanoxerine with two equivalents of hydrogen chloride. Potent, competitive inhibitor of dopamine uptake (Ki = 1 nM for inhibition of striatal dopamine uptake). Has > 100-fold lower affinity for the noradrenalin and 5-HT uptake carriers. Also a potent sigma ligand (IC50 = 48 nM). Centrally active following systemic administration. It has a role as a dopamine uptake inhibitor. It contains a vanoxerine(2+).
Source: ChEBI
| Molecular formula | C28H34Cl2F2N2O |
|---|---|
| Molecular weight | 523.5 g/mol |
| IUPAC name | 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine;dihydrochloride |
| InChIKey | MIBSKSYCRFWIRU-UHFFFAOYSA-N |
| SMILES | C1CN(CCN1CCCC2=CC=CC=C2)CCOC(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F.Cl.Cl |
Computed by PubChem (NCBI)