GDC–0326
cas: 1282514-88-8 — see every product listed under this CAS number, including other names
GDC–0326 (CAS 1282514-88-8) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 100mg, 25mg, 5mg, 50mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC19161-10 |
| cas | 1282514-88-8 |
| size | 10mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 10mg | 1037.01 Pln | |
| GLPBio | 100mg | 4800.13 Pln | |
| GLPBio | 25mg | 1729.72 Pln | |
| GLPBio | 5mg | 760.86 Pln | |
| GLPBio | 50mg | 2890.48 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
GDC-0326 is an organic heterotricyclic compound that is 5,6-dihydroimidazo[1,2-d][1,4]benzoxazepine substituted by 1-(propan-2-yl)-1H-1,2,4-triazol-5-yl and [(2S)-1-amino-1-oxopropan-2-yl]oxy groups at positions 2 and 9, respectively. It is a potent and selective inhibitor of PI3Kalpha (Ki = 0.2 nM). It has a role as an antineoplastic agent and an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor. It is a primary carboxamide, an ether, an organic heterotricyclic compound, a member of triazoles and a tertiary amino compound.
Source: ChEBI
| Molecular formula | C19H22N6O3 |
|---|---|
| Molecular weight | 382.4 g/mol |
| IUPAC name | (2S)-2-[[2-(2-propan-2-yl-1,2,4-triazol-3-yl)-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl]oxy]propanamide |
| InChIKey | SIKYDKLGPWRPMZ-LBPRGKRZSA-N |
| SMILES | C[C@@H](C(=O)N)OC1=CC2=C(C=C1)C3=NC(=CN3CCO2)C4=NC=NN4C(C)C |
Computed by PubChem (NCBI)