Products 1282514-88-8
CAS 1282514-88-8 appears in our catalog under these names: GDC-0326, 98%, GDC-0326/ 99.79% (existing batch purity), GDC–0326, GDC-0326, GDC-0326, ≥98%, ≥98%. Offered by: AmBeed, TargetMol, GLPBio, Biosynth, Chemat. Available pack sizes: 25mg, 5mg, 10mg, 50mg, 100mg, 200mg, 2mg, 25 mg.
GDC-0326 is an organic heterotricyclic compound that is 5,6-dihydroimidazo[1,2-d][1,4]benzoxazepine substituted by 1-(propan-2-yl)-1H-1,2,4-triazol-5-yl and [(2S)-1-amino-1-oxopropan-2-yl]oxy groups at positions 2 and 9, respectively. It is a potent and selective inhibitor of PI3Kalpha (Ki = 0.2 nM). It has a role as an antineoplastic agent and an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor. It is a primary carboxamide, an ether, an organic heterotricyclic compound, a member of triazoles and a tertiary amino compound.
Source: ChEBI
| Molecular formula | C19H22N6O3 |
|---|---|
| Molecular weight | 382.4 g/mol |
| IUPAC name | (2S)-2-[[2-(2-propan-2-yl-1,2,4-triazol-3-yl)-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl]oxy]propanamide |
| InChIKey | SIKYDKLGPWRPMZ-LBPRGKRZSA-N |
| SMILES | C[C@@H](C(=O)N)OC1=CC2=C(C=C1)C3=NC(=CN3CCO2)C4=NC=NN4C(C)C |
Computed by PubChem (NCBI)