GDC-0326

cas: 1282514-88-8 — see every product listed under this CAS number, including other names

GDC-0326 (CAS 1282514-88-8) is a chemical reagent available from Chemat. Available pack sizes: 50mg, 25mg. Offered by: Biosynth.

brandBiosynth
catalog numberHBC51488-50mg
cas1282514-88-8
size50mg
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Available pack sizes

brand size price
Biosynth 50mg price on request
Biosynth 25mg price on request

properties

categoryLife Sciences
purityNo data
delivery time3-4 Weeks
Structural formula: {0} (CAS {1})

GDC-0326 is an organic heterotricyclic compound that is 5,6-dihydroimidazo[1,2-d][1,4]benzoxazepine substituted by 1-(propan-2-yl)-1H-1,2,4-triazol-5-yl and [(2S)-1-amino-1-oxopropan-2-yl]oxy groups at positions 2 and 9, respectively. It is a potent and selective inhibitor of PI3Kalpha (Ki = 0.2 nM). It has a role as an antineoplastic agent and an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor. It is a primary carboxamide, an ether, an organic heterotricyclic compound, a member of triazoles and a tertiary amino compound.

Source: ChEBI

Identity
Molecular formulaC19H22N6O3
Molecular weight382.4 g/mol
IUPAC name(2S)-2-[[2-(2-propan-2-yl-1,2,4-triazol-3-yl)-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl]oxy]propanamide
InChIKeySIKYDKLGPWRPMZ-LBPRGKRZSA-N
SMILESC[C@@H](C(=O)N)OC1=CC2=C(C=C1)C3=NC(=CN3CCO2)C4=NC=NN4C(C)C

Computed by PubChem (NCBI)

Synonyms: orb1226615, orb1303474, SIKYDKLGPWRPMZ-LBPRGKRZSA-N

Also listed as

GDC-0326, 98% AmBeed CAS 1282514-88-8
GDC-0326/ 99.79% (existing batch purity) TargetMol CAS 1282514-88-8
GDC–0326 GLPBio CAS 1282514-88-8
GDC-0326, ≥98%, ≥98% Chemat CAS 1282514-88-8
GDC-0326, 99.92% MedChemExpress CAS 1282514-88-8