GR127935, 99.33%
cas: 148672-13-3 — see every product listed under this CAS number, including other names
GR127935, 99.33% (CAS 148672-13-3) is a chemical reagent available from Chemat. Available pack sizes: 5 mg, 10 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-123869-5 mg |
| cas | 148672-13-3 |
| size | 5 mg |
| availability | In stock |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 5 mg | 695.86 Pln | |
| MedChemExpress | 10 mg | 1081.31 Pln |
properties
| delivery time | 2-3 weeks |
|---|---|
| purity | 99.33% |
GR 127935 is a member of the class of benzamides obtained by formal condensation of the carboxy group of 2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-carboxylic acid and the anilino group of 4-methoxy-3-(4-methylpiperazin-1-yl)aniline. Potent and selective 5-HT1B/1D receptor antagonist (pKi values are 8.5 for both guinea pig 5-HT1D and rat 5-HT1B receptors). Displays > 100-fold selectivity over 5HT1A, 5-HT2A, 5-HT2C receptors and other receptor types. Centrally active following oral administration. It has a role as a serotonergic antagonist. It is a member of benzamides, a 1,2,4-oxadiazole, a N-alkylpiperazine and a N-arylpiperazine. It is a conjugate base of a GR 127935(1+).
Source: ChEBI
| Molecular formula | C29H31N5O3 |
|---|---|
| Molecular weight | 497.6 g/mol |
| IUPAC name | N-[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]-4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]benzamide |
| InChIKey | YDBCEBYHYKAFRX-UHFFFAOYSA-N |
| SMILES | CC1=C(C=CC(=C1)C2=NOC(=N2)C)C3=CC=C(C=C3)C(=O)NC4=CC(=C(C=C4)OC)N5CCN(CC5)C |
Computed by PubChem (NCBI)