GS 441524

cas: 1191237-69-0 — see every product listed under this CAS number, including other names

GS 441524 (CAS 1191237-69-0) is a chemical reagent available from Chemat. Available pack sizes: 0,25g, 1g, 5g. Offered by: Biosynth.

brandBiosynth
catalog numberAG167808-0,25g
cas1191237-69-0
size0,25g
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properties

categoryAntimicrobials
sub-category 1Antivirals
purityNo data
delivery time1-2 weeks
Structural formula: {0} (CAS {1})

GS-441524 is a C-nucleoside analog that is (2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile substituted by a 4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl group at position 2. It is the active metabolite of remdesivir and exhibits a broad range of inhibitory activity against various RNA viruses including HCV, parainfluenza and SARS-CoV. It has a role as an anticoronaviral agent, an antiviral agent and a drug metabolite. It is a nitrile, an aromatic amine, a C-nucleoside and a pyrrolotriazine.

Source: ChEBI

Identity
Molecular formulaC12H13N5O4
Molecular weight291.26 g/mol
IUPAC name(2R,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)oxolane-2-carbonitrile
InChIKeyBRDWIEOJOWJCLU-LTGWCKQJSA-N
SMILESC1=C2C(=NC=NN2C(=C1)[C@]3([C@@H]([C@@H]([C@H](O3)CO)O)O)C#N)N

Computed by PubChem (NCBI)

Synonyms: 2-C-(4-Aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-2,5-anhydro-D-altrononitrile, D-Altrononitrile, 2-C-(4-aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-2,5-anhydro-, Remdesivir Impurity 5, reacted form, Nucleoside of Remdesivir, orb1220543, orb1299964, BRDWIEOJOWJCLU-LTGWCKQJSA-N, Remdesivir metabolite(GS-441524), Remdesivir metabolite(GS-441524)?
Related forms of this compound
(2R,3R,4S,5R)-2-(5-deuterio-4-imino-1H-pyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)oxolane-2-carbonitrile C12H13N5O4
(2R,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)oxolane-2-carbonitrile C12H13N5O4
(2S,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)oxolane-2-carbonitrile C12H13N5O4
Isomers (same molecular formula)
(2R,3S,4R,5R)-2-(hydroxymethyl)-5-imidazo[2,1-f]purin-3-yloxolane-3,4-diol C12H13N5O4
2-[[[2-(methoxymethyl)-1,2,4-triazol-3-yl]amino]carbamoyl]benzoic acid C12H13N5O4
1-[(4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5H-imidazo[2,1-b]purin-4-one C12H13N5O4

Also listed as

Remdesivir Impurity 6 Chemat Brand CAS 1191237-69-0
Remdesivir Related Compound 6 (GS-441524) Chemat Brand CAS 1191237-69-0
(2R,3R,4S,5R)-2-(4-Aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile, >95% (HPLC) TRC CAS 1191237-69-0
2-C-(4-Aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-2,5-anhydro-D-altrononitrile Mikromol CAS 1191237-69-0
GS–441524 GLPBio CAS 1191237-69-0
GS-441524/ 99.9% TargetMol CAS 1191237-69-0
GS-441524 (Remdesivir Metabolite), 98.00% Chemat CAS 1191237-69-0
GS-441524 99% Ambeed CAS 1191237-69-0
(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile, 99%, 99% Chemat CAS 1191237-69-0
GS-441524, 99.94% MedChemExpress CAS 1191237-69-0
(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile, 98% Fluorochem CAS 1191237-69-0