(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile, 99%

cas: 1191237-69-0 — see every product listed under this CAS number, including other names

(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile, 99% (CAS 1191237-69-0) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 10mg, 100mg, 250mg, 1g, 5g, 10g, 25g. Offered by: Chemat, BLDpharm.

brandChemat
catalog numberCh12FW28-1mg
cas1191237-69-0
size1mg
availability 1000g
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Available pack sizes

brand size price
Chemat 1mg 88.40 Pln
Chemat 10mg 88.40 Pln
Chemat 100mg 112.40 Pln
Chemat 250mg 131.60 Pln
Chemat 1g 146.00 Pln
Chemat 5g 477.20 Pln
Chemat 10g 650.00 Pln
Chemat 25g 1302.80 Pln
Chemat 50g 2128.40 Pln
Chemat 100g 3506.00 Pln
BLDpharm 50mg 186.63 Pln
BLDpharm 100mg 208.84 Pln
BLDpharm 250mg 236.61 Pln
BLDpharm 1g 353.23 Pln
BLDpharm 5g 1097.42 Pln
BLDpharm 10g 1897.13 Pln
BLDpharm 25g 3724.27 Pln

properties

purity99%
delivery time3 weeks
Structural formula: {0} (CAS {1})

GS-441524 is a C-nucleoside analog that is (2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile substituted by a 4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl group at position 2. It is the active metabolite of remdesivir and exhibits a broad range of inhibitory activity against various RNA viruses including HCV, parainfluenza and SARS-CoV. It has a role as an anticoronaviral agent, an antiviral agent and a drug metabolite. It is a nitrile, an aromatic amine, a C-nucleoside and a pyrrolotriazine.

Source: ChEBI

Identity
Molecular formulaC12H13N5O4
Molecular weight291.26 g/mol
IUPAC name(2R,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)oxolane-2-carbonitrile
InChIKeyBRDWIEOJOWJCLU-LTGWCKQJSA-N
SMILESC1=C2C(=NC=NN2C(=C1)[C@]3([C@@H]([C@@H]([C@H](O3)CO)O)O)C#N)N

Computed by PubChem (NCBI)

Synonyms: 2-C-(4-Aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-2,5-anhydro-D-altrononitrile, D-Altrononitrile, 2-C-(4-aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-2,5-anhydro-, Remdesivir Impurity 5, reacted form, Nucleoside of Remdesivir, orb1220543, orb1299964, BRDWIEOJOWJCLU-LTGWCKQJSA-N, Remdesivir metabolite(GS-441524), Remdesivir metabolite(GS-441524)?
Related forms of this compound
(2R,3R,4S,5R)-2-(5-deuterio-4-imino-1H-pyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)oxolane-2-carbonitrile C12H13N5O4
(2R,3R,4R,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)oxolane-2-carbonitrile C12H13N5O4
(2S,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)oxolane-2-carbonitrile C12H13N5O4
Isomers (same molecular formula)
(2R,3S,4R,5R)-2-(hydroxymethyl)-5-imidazo[2,1-f]purin-3-yloxolane-3,4-diol C12H13N5O4
2-[[[2-(methoxymethyl)-1,2,4-triazol-3-yl]amino]carbamoyl]benzoic acid C12H13N5O4
1-[(4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5H-imidazo[2,1-b]purin-4-one C12H13N5O4
4-amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carbonitrile C12H13N5O4
methyl N-[5-(3,6-dihydro-2H-pyridin-1-yl)-2-oxo-[1,2,4]oxadiazolo[2,3-a]pyrimidin-7-yl]carbamate C12H13N5O4
3-[(2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4H-imidazo[1,2-a]purin-9-one C12H13N5O4
(2R,3R,4S,5R)-2-(6-amino-2-ethynylpurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol C12H13N5O4
2-amino-7-[(2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-oxo-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile C12H13N5O4
4-amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrrolo[2,3-d]pyrimidine-5-carbonitrile C12H13N5O4

Also listed as

Remdesivir Impurity 6 Chemat Brand CAS 1191237-69-0
Remdesivir Related Compound 6 (GS-441524) Chemat Brand CAS 1191237-69-0
(2R,3R,4S,5R)-2-(4-Aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile, >95% (HPLC) TRC CAS 1191237-69-0
2-C-(4-Aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-2,5-anhydro-D-altrononitrile Mikromol CAS 1191237-69-0
GS–441524 GLPBio CAS 1191237-69-0
GS-441524/ 99.9% TargetMol CAS 1191237-69-0
GS-441524 (Remdesivir Metabolite), 98.00% Chemat CAS 1191237-69-0
GS 441524 Biosynth CAS 1191237-69-0
(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile, 99%, 99% Chemat CAS 1191237-69-0
GS-441524, 99.94% MedChemExpress CAS 1191237-69-0
GS-441524, 99% Ambeed CAS 1191237-69-0
(2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile, 98% (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile, 98% Fluorochem CAS 1191237-69-0

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