cas: 1187431-43-1 — see every product listed under this CAS number, including other names
GSK 1120212B (CAS 1187431-43-1) is a chemical reagent available from Chemat. Available pack sizes: 250mg, 100mg, 500mg. Offered by: Biosynth.
| brand | Biosynth |
|---|---|
| catalog number | FT65193-250mg |
| cas | 1187431-43-1 |
| size | 250mg |
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| brand | size | price | |
|---|---|---|---|
| Biosynth | 250mg | price on request | |
| Biosynth | 100mg | price on request | |
| Biosynth | 500mg | price on request |
| category | Life Sciences |
|---|---|
| sub-category 1 | Ligands |
| sub-category 2 | Enzyme Modulators |
| purity | No data |
| delivery time | 1-2 weeks |
Trametinib dimethyl sulfoxide is an addition compound obtained by combining equimolar amounts of trametinib and dimethyl sulfoxide. Used for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations, and who have not received prior BRAF inhibitor treatment. It has a role as an antineoplastic agent and an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor. It contains a dimethyl sulfoxide and a trametinib.
Source: ChEBI
| Molecular formula | C28H29FIN5O5S |
|---|---|
| Molecular weight | 693.5 g/mol |
| IUPAC name | N-[3-[3-cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide;methylsulfinylmethane |
| InChIKey | OQUFJVRYDFIQBW-UHFFFAOYSA-N |
| SMILES | CC1=C2C(=C(N(C1=O)C)NC3=C(C=C(C=C3)I)F)C(=O)N(C(=O)N2C4=CC=CC(=C4)NC(=O)C)C5CC5.CS(=O)C |
Computed by PubChem (NCBI)