Trametinib DMSO solvate

cas: 1187431-43-1 — see every product listed under this CAS number, including other names

Trametinib DMSO solvate (CAS 1187431-43-1) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 100mg, 10mM (in 1ml dmso), 50mg. Offered by: GLPBio.

brandGLPBio
catalog numberGC15260-10
cas1187431-43-1
size10mg
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Available pack sizes

brand size price
GLPBio 10mg 817.02 Pln
GLPBio 100mg 1804.61 Pln
GLPBio 10mM (in 1ml dmso) 859.15 Pln
GLPBio 50mg 1238.27 Pln

properties

purityNo data
delivery timeTo be confirmed by Chemat

Trametinib dimethyl sulfoxide is an addition compound obtained by combining equimolar amounts of trametinib and dimethyl sulfoxide. Used for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations, and who have not received prior BRAF inhibitor treatment. It has a role as an antineoplastic agent and an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor. It contains a dimethyl sulfoxide and a trametinib.

Source: ChEBI

Identity
Molecular formulaC28H29FIN5O5S
Molecular weight693.5 g/mol
IUPAC nameN-[3-[3-cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide;methylsulfinylmethane
InChIKeyOQUFJVRYDFIQBW-UHFFFAOYSA-N
SMILESCC1=C2C(=C(N(C1=O)C)NC3=C(C=C(C=C3)I)F)C(=O)N(C(=O)N2C4=CC=CC(=C4)NC(=O)C)C5CC5.CS(=O)C

Computed by PubChem (NCBI)

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