GSK461364 98+%

cas: 929095-18-1 — see every product listed under this CAS number, including other names

GSK461364 98+% (CAS 929095-18-1) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 2mg, 5mg, 10mg, 50mg, 100mg, 250mg, 1g. Offered by: Ambeed.

brandAmbeed
catalog numberA313486-1mg
cas929095-18-1
size1mg
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Available pack sizes

brand size price
Ambeed 1mg 197.94 Pln
Ambeed 2mg 242.44 Pln
Ambeed 5mg 320.31 Pln
Ambeed 10mg 453.81 Pln
Ambeed 50mg 1071.25 Pln
Ambeed 100mg 1727.62 Pln
Ambeed 250mg 2890.19 Pln
Ambeed 1g 7440.31 Pln

properties

purity98+%
delivery time 1-2 weeks
ambeed catalog no.A313486
Structural formula: {0} (CAS {1})

GSK461364 is a member of the class of benzimidazoles that is 1H-benzimidazole substituted by 5-carbamoyl-4-{(1R)-1-[2-(trifluoromethyl)phenyl]ethoxy}thiophen-2-yl and (4-methylpiperazin-1-yl)methyl groups at positions 1 and 6, respectively. It is an ATP-competitive polo-like kinase 1 (PLK1) inhibitor (Ki = 2.2 nM). It has a role as an EC 2.7.11.21 (polo kinase) inhibitor, an antineoplastic agent and an apoptosis inducer. It is a primary carboxamide, a member of benzimidazoles, an ether, a member of thiophenes, a N-methylpiperazine and a member of (trifluoromethyl)benzenes.

Source: ChEBI

Identity
Molecular formulaC27H28F3N5O2S
Molecular weight543.6 g/mol
IUPAC name5-[6-[(4-methylpiperazin-1-yl)methyl]benzimidazol-1-yl]-3-[(1R)-1-[2-(trifluoromethyl)phenyl]ethoxy]thiophene-2-carboxamide
InChIKeyZHJGWYRLJUCMRT-QGZVFWFLSA-N
SMILESC[C@H](C1=CC=CC=C1C(F)(F)F)OC2=C(SC(=C2)N3C=NC4=C3C=C(C=C4)CN5CCN(CC5)C)C(=O)N

Computed by PubChem (NCBI)

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