GW-843682X

cas: 660868-91-7 — see every product listed under this CAS number, including other names

GW-843682X (CAS 660868-91-7) is a chemical reagent available from Chemat. Available pack sizes: 500mg. Offered by: TRC.

brandTRC
catalog numberTRC-G931535-500MG
cas660868-91-7
size500mg
Need more information?

Ask us about this product — we're happy to help.

Available pack sizes

brand size price
TRC 500mg price on request

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

GW843682X is a member of the class of benzimidazoles that is 1H-benzimidazole substituted by 5-carbamoyl-4-{[2-(trifluoromethyl)phenyl]methoxy}thiophen-2-yl, methoxy, and methoxy groups at positions 1, 5, and 6, respectively. It is a potent inhibitor of PLK1 and PLK3 (IC50 = 2.2 and 9.1 nM respectively). It has a role as an EC 2.7.11.21 (polo kinase) inhibitor, an antineoplastic agent and an apoptosis inducer. It is a primary carboxamide, a member of benzimidazoles, a member of thiophenes, an aromatic ether and a member of (trifluoromethyl)benzenes.

Source: ChEBI

Identity
Molecular formulaC22H18F3N3O4S
Molecular weight477.5 g/mol
IUPAC name5-(5,6-dimethoxybenzimidazol-1-yl)-3-[[2-(trifluoromethyl)phenyl]methoxy]thiophene-2-carboxamide
InChIKeyJSKUWFIZUALZLX-UHFFFAOYSA-N
SMILESCOC1=C(C=C2C(=C1)N=CN2C3=CC(=C(S3)C(=O)N)OCC4=CC=CC=C4C(F)(F)F)OC

Computed by PubChem (NCBI)

Synonyms: Kinome_3462, thiophene deriv., 20, orb1220159, orb1308238, s2880

Also listed as

GW843682X/ 99.56% (existing batch purity) TargetMol CAS 660868-91-7
GW843682X GLPBio CAS 660868-91-7
GW843682X 98% Ambeed CAS 660868-91-7
5-(5,6-Dimethoxy-1H-benzo[d]imidazol-1-yl)-3-((2-(trifluoromethyl)benzyl)oxy)thiophene-2-carboxamide Chemat CAS 660868-91-7
GW843682X, 99.89% MedChemExpress CAS 660868-91-7