GW843682X, 99.89%
cas: 660868-91-7 — see every product listed under this CAS number, including other names
GW843682X, 99.89% (CAS 660868-91-7) is a chemical reagent available from Chemat. Available pack sizes: 10mM/1mL, 50 mg, 10 mg, 5 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-11003-10mM/1mL |
| cas | 660868-91-7 |
| size | 10mM/1mL |
| availability | In stock |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 10mM/1mL | 602.98 Pln | |
| MedChemExpress | 50 mg | 2971.42 Pln | |
| MedChemExpress | 10 mg | 876.97 Pln | |
| MedChemExpress | 5 mg | 561.18 Pln |
properties
| delivery time | 1-2 weeks |
|---|---|
| purity | 99.89% |
GW843682X is a member of the class of benzimidazoles that is 1H-benzimidazole substituted by 5-carbamoyl-4-{[2-(trifluoromethyl)phenyl]methoxy}thiophen-2-yl, methoxy, and methoxy groups at positions 1, 5, and 6, respectively. It is a potent inhibitor of PLK1 and PLK3 (IC50 = 2.2 and 9.1 nM respectively). It has a role as an EC 2.7.11.21 (polo kinase) inhibitor, an antineoplastic agent and an apoptosis inducer. It is a primary carboxamide, a member of benzimidazoles, a member of thiophenes, an aromatic ether and a member of (trifluoromethyl)benzenes.
Source: ChEBI
| Molecular formula | C22H18F3N3O4S |
|---|---|
| Molecular weight | 477.5 g/mol |
| IUPAC name | 5-(5,6-dimethoxybenzimidazol-1-yl)-3-[[2-(trifluoromethyl)phenyl]methoxy]thiophene-2-carboxamide |
| InChIKey | JSKUWFIZUALZLX-UHFFFAOYSA-N |
| SMILES | COC1=C(C=C2C(=C1)N=CN2C3=CC(=C(S3)C(=O)N)OCC4=CC=CC=C4C(F)(F)F)OC |
Computed by PubChem (NCBI)