Products 184475-35-2

CAS 184475-35-2 appears in our catalog under these names: Gefitinib, Gefitinib, >95% (HPLC), Gefitinib/ 100%, Gefitinib (ZD1839), Gefitinib, 99.00%. Offered by: Chemat Brand, TRC, Mikromol, TargetMol, GLPBio. Available pack sizes: on request, 100mg, 250mg, 500mg, 1g, 5g, 10mM (in 1ml dmso), 10mg.

Gefitinib
Chemat Brand, Mikromol, Biosynth
  • size: on request, 250mg, 5g, 10g
  • Variants: 7
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Gefitinib, >95% (HPLC)
TRC
  • size: 100mg, 250mg, 500mg
  • Variants: 3
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Gefitinib/ 100%
TargetMol
  • size: 1g, 5g, 100mg, 500mg
  • Variants: 4
from 511.92
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Gefitinib (ZD1839)
GLPBio
  • size: 100mg, 250mg, 10mM (in 1ml dmso)
  • Variants: 3
from 648.53
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Gefitinib, 99.00%
Chemat
  • size: 100mg, 250mg, 500mg
  • Variants: 3
from 276.06
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Gefitinib, >98.0%(HPLC)(T)
TCI
  • size: 1g, 5g
  • Variants: 2
from 182.27
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Gefitinib - Bio-X â„¢
Biosynth
  • size: 10mg
  • Variants: 1
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Gefitinib, 98%
Thermo Scientific (Acros)
  • size: 1g, 5g
  • Variants: 2
from 134.97
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Gefitinib 98%
Ambeed
  • size: 250mg, 1g, 5g, 10g
  • Variants: 6
from 131.19
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N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine, 98%, 98%
Chemat
  • size: 250mg, 5g, 10g, 25g
  • Variants: 5
from 74.00
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Gefitinib, BioScience Grade, 10 mg
Roth
  • size: 10mg
  • Variants: 1
from 514.44
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N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine, 98%
Chemat
  • size: 1g
  • Variants: 1
from 83.60
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Gefitinib, 99.99%
MedChemExpress
  • size: 10mM/1mL, 500 mg, 5 g, 1 g
  • Variants: 5
from 407.93
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Gefitinib (GMP), 100.00%
MedChemExpress
  • size: 10 mg, 100 mg, 50 mg
  • Variants: 3
from 5302.70
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Gefitinib (Standard), 99.94%
MedChemExpress
  • size: 10 mg, 25 mg, 100 mg, 50 mg
  • Variants: 4
from 291.83
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N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine, 98%
Fluorochem
  • size: 250mg, 1g, 5g, 10g
  • Variants: 6
from 102.07
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Structural formula: {0} (CAS {1})

Gefitinib is a member of the class of quinazolines that is quinazoline which is substituted by a (3-chloro-4-fluorophenyl)nitrilo group, 3-(morpholin-4-yl)propoxy group and a methoxy group at positions 4,6 and 7, respectively. An EGFR kinase inhibitor used for the treatment of non-small cell lung cancer. It has a role as an antineoplastic agent and an epidermal growth factor receptor antagonist. It is an aromatic ether, a member of quinazolines, a member of morpholines, a secondary amino compound, a tertiary amino compound, a member of monochlorobenzenes and a member of monofluorobenzenes.

Source: ChEBI

Identity
Molecular formulaC22H24ClFN4O3
Molecular weight446.9 g/mol
IUPAC nameN-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine
InChIKeyXGALLCVXEZPNRQ-UHFFFAOYSA-N
SMILESCOC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4

Computed by PubChem (NCBI)

Synonyms: Gefitinib, Iressa, Irressat, gefitinibum, 4-(3'-Chloro-4'-fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline, N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholinopropoxy)quinazolin-4-amine, gefitinib (zd1839), C22H24ClFN4O3, Gefitinib (GMP), Gefitinib [USAN:INN:BAN]
Related forms of this compound
N-(3-chloro-4-fluorophenyl)-6-(1,1,2,2,3,3-hexadeuterio-3-morpholin-4-ylpropoxy)-7-methoxyquinazolin-4-amine C22H24ClFN4O3
N-(3-chloro-4-fluorophenyl)-6-(3-morpholin-4-ylpropoxy)-7-(trideuteriomethoxy)quinazolin-4-amine C22H24ClFN4O3
N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(2,2,3,3,5,5,6,6-octadeuteriomorpholin-4-yl)propoxy]quinazolin-4-amine C22H24ClFN4O3
Isomers (same molecular formula)
N-(4-chloro-3-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine C22H24ClFN4O3