Givinostat (ITF–2357)
cas: 497833-27-9 — see every product listed under this CAS number, including other names
Givinostat (ITF–2357) (CAS 497833-27-9) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 100mg, 2mg, 5mg, 50mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC33050-10 |
| cas | 497833-27-9 |
| size | 10mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 10mg | 1444.21 Pln | |
| GLPBio | 100mg | 5577.09 Pln | |
| GLPBio | 2mg | 845.11 Pln | |
| GLPBio | 5mg | 1060.41 Pln | |
| GLPBio | 50mg | 3512.99 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Givinostat is a member of the class of naphthalenes that is naphthalene substituted by ({[4-(hydroxycarbamoyl)phenyl]carbamoyl}oxy)methyl and (diethylamino)methyl groups at positions 2 and 6, respectively. It is a histone deacetylase inhibitor indicated for individuals diagnosed with Duchenne muscular dystrophy. It has a role as an antineoplastic agent, an angiogenesis inhibitor, an EC 3.5.1.98 (histone deacetylase) inhibitor, an anti-inflammatory agent and an apoptosis inducer. It is a member of benzenes, a carbamate ester, a hydroxamic acid, a member of naphthalenes and a tertiary amino compound. It is a conjugate base of a givinostat(1+).
Source: ChEBI
| Molecular formula | C24H27N3O4 |
|---|---|
| Molecular weight | 421.5 g/mol |
| IUPAC name | [6-(diethylaminomethyl)naphthalen-2-yl]methyl N-[4-(hydroxycarbamoyl)phenyl]carbamate |
| InChIKey | YALNUENQHAQXEA-UHFFFAOYSA-N |
| SMILES | CCN(CC)CC1=CC2=C(C=C1)C=C(C=C2)COC(=O)NC3=CC=C(C=C3)C(=O)NO |
Computed by PubChem (NCBI)