Products 497833-27-9
CAS 497833-27-9 appears in our catalog under these names: Givinostat, Givinostat (ITF–2357), Givinostat 99+%, (6-((Diethylamino)methyl)naphthalen-2-yl)methyl (4-(hydroxycarbamoyl)phenyl)carbamate, 99+%, 99+%, Givinostat, 98.67%. Offered by: Chemat Brand, GLPBio, Ambeed, Chemat, MedChemExpress. Available pack sizes: on request, 10mg, 100mg, 2mg, 5mg, 50mg, 25mg, 250mg.
Givinostat is a member of the class of naphthalenes that is naphthalene substituted by ({[4-(hydroxycarbamoyl)phenyl]carbamoyl}oxy)methyl and (diethylamino)methyl groups at positions 2 and 6, respectively. It is a histone deacetylase inhibitor indicated for individuals diagnosed with Duchenne muscular dystrophy. It has a role as an antineoplastic agent, an angiogenesis inhibitor, an EC 3.5.1.98 (histone deacetylase) inhibitor, an anti-inflammatory agent and an apoptosis inducer. It is a member of benzenes, a carbamate ester, a hydroxamic acid, a member of naphthalenes and a tertiary amino compound. It is a conjugate base of a givinostat(1+).
Source: ChEBI
| Molecular formula | C24H27N3O4 |
|---|---|
| Molecular weight | 421.5 g/mol |
| IUPAC name | [6-(diethylaminomethyl)naphthalen-2-yl]methyl N-[4-(hydroxycarbamoyl)phenyl]carbamate |
| InChIKey | YALNUENQHAQXEA-UHFFFAOYSA-N |
| SMILES | CCN(CC)CC1=CC2=C(C=C1)C=C(C=C2)COC(=O)NC3=CC=C(C=C3)C(=O)NO |
Computed by PubChem (NCBI)