Granisetron

cas: 109889-09-0 — see every product listed under this CAS number, including other names

Granisetron (CAS 109889-09-0) is a chemical reagent available from Chemat. Available pack sizes: 100mg, 5mg, 50mg. Offered by: GLPBio.

brandGLPBio
catalog numberGC12398-100
cas109889-09-0
size100mg
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Available pack sizes

brand size price
GLPBio 100mg 840.43 Pln
GLPBio 5mg 597.04 Pln
GLPBio 50mg 643.84 Pln

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Granisetron is a monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 1-methyl-1H-indazole-3-carboxylic acid with the primary amino group of (3-endo)-9-methyl-9-azabicyclo[3.3.1]nonan-3-amine. A selective 5-HT3 receptor antagonist, it is used (generally as the monohydrochloride salt) to manage nausea and vomiting caused by cancer chemotherapy and radiotherapy, and to prevent and treat postoperative nausea and vomiting. It has a role as a serotonergic antagonist and an antiemetic. It is a monocarboxylic acid amide, a member of indazoles and a tertiary amino compound.

Source: ChEBI

Identity
Molecular formulaC18H24N4O
Molecular weight312.4 g/mol
IUPAC name1-methyl-N-[(1R,5S)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]indazole-3-carboxamide
InChIKeyMFWNKCLOYSRHCJ-AGUYFDCRSA-N
SMILESCN1[C@@H]2CCC[C@H]1CC(C2)NC(=O)C3=NN(C4=CC=CC=C43)C

Computed by PubChem (NCBI)

Synonyms: Granisetron (JAN/USAN/INN), granisetron, Sancuso, Sustol, exo-Granisetron, Kevatril, Granisetronum, Kytril, Granisetron EP Impurity F, Granisetronum [INN-Latin]
Related forms of this compound
1-methyl-N-[(1R,5S)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]indazole-3-carboxamide C18H24N4O
N-[(1R,5S)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]-1-(trideuteriomethyl)indazole-3-carboxamide C18H24N4O
1-methyl-N-[9-(trideuteriomethyl)-9-azabicyclo[3.3.1]nonan-3-yl]indazole-3-carboxamide C18H24N4O
Isomers (same molecular formula)
N-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]pyridin-2-amine C18H24N4O
2-methyl-N-(9-methyl-9-azabicyclo[3.3.1]nonan-3-yl)indazole-3-carboxamide C18H24N4O
(2R,3R)-3-(4-methylidenepiperidin-1-yl)-2-phenyl-1-(1,2,4-triazol-1-yl)butan-2-ol C18H24N4O
1-(4-amino-2-butylimidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol C18H24N4O
(1R,5S)-N-[2-(1,7-dimethylindazol-3-yl)propan-2-yl]-3-azabicyclo[3.1.0]hexane-6-carboxamide C18H24N4O
7-(cyclobutylmethyl)-3-(1-cyclopropylcyclopropyl)-5,6-dimethyl-[1,2,4]triazolo[4,3-a]pyrazin-8-one C18H24N4O

Also listed as

Granisetron, >95% (HPLC) TRC CAS 109889-09-0
1-Methyl-N-(9-methyl-9-azabicyclo(3.3.1)non-3-yl)-indazole-3-carboxamide Biosynth CAS 109889-09-0
Granisetron, 98%, 98% Chemat CAS 109889-09-0
Granisetron, 99.95% MedChemExpress CAS 109889-09-0
Granisetron (Standard) MedChemExpress CAS 109889-09-0