Products 109889-09-0
CAS 109889-09-0 appears in our catalog under these names: Granisetron, >95% (HPLC), Granisetron, 1-Methyl-N-(9-methyl-9-azabicyclo(3.3.1)non-3-yl)-indazole-3-carboxamide, Granisetron, 98%, 98%, Granisetron, 99.95%. Offered by: TRC, GLPBio, Biosynth, Chemat, MedChemExpress. Available pack sizes: 25mg, 50mg, 100mg, 5mg, 250mg, 500mg, 1000mg, 2000mg.
Granisetron is a monocarboxylic acid amide resulting from the formal condensation of the carboxy group of 1-methyl-1H-indazole-3-carboxylic acid with the primary amino group of (3-endo)-9-methyl-9-azabicyclo[3.3.1]nonan-3-amine. A selective 5-HT3 receptor antagonist, it is used (generally as the monohydrochloride salt) to manage nausea and vomiting caused by cancer chemotherapy and radiotherapy, and to prevent and treat postoperative nausea and vomiting. It has a role as a serotonergic antagonist and an antiemetic. It is a monocarboxylic acid amide, a member of indazoles and a tertiary amino compound.
Source: ChEBI
| Molecular formula | C18H24N4O |
|---|---|
| Molecular weight | 312.4 g/mol |
| IUPAC name | 1-methyl-N-[(1R,5S)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]indazole-3-carboxamide |
| InChIKey | MFWNKCLOYSRHCJ-AGUYFDCRSA-N |
| SMILES | CN1[C@@H]2CCC[C@H]1CC(C2)NC(=O)C3=NN(C4=CC=CC=C43)C |
Computed by PubChem (NCBI)