CAS 53-86-1 appears in our catalog under these names: Indomethacin, Acemetacin Impurity 2（Acemetacin EP Impurity B）, Indomethacin, >95% (HPLC), Indometacin, Indometacin 1.0 mg/ml in Acetonitrile. Offered by: Chemat Brand, Hubei YoungXin, TRC, Mikromol, LoGiCal. Available pack sizes: on request, 10mg, 25mg, 50mg, 100mg, 200mg, 1g, 5g.
Indometacin is a member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis. It has a role as a non-steroidal anti-inflammatory drug, an analgesic, an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor, a xenobiotic, a gout suppressant, a drug metabolite, a xenobiotic metabolite and an environmental contaminant. It is a member of indole-3-acetic acids, an aromatic ether, a N-acylindole and a member of monochlorobenzenes.
Source: ChEBI
| Molecular formula | C19H16ClNO4 |
|---|---|
| Molecular weight | 357.8 g/mol |
| IUPAC name | 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid |
| InChIKey | CGIGDMFJXJATDK-UHFFFAOYSA-N |
| SMILES | CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O |
Computed by PubChem (NCBI)