Irinotecan HCl 98%

cas: 100286-90-6 — see every product listed under this CAS number, including other names

Irinotecan HCl 98% (CAS 100286-90-6) is a chemical reagent available from Chemat. Available pack sizes: 10g, 50mg, 100mg, 250mg, 1g, 5g. Offered by: Ambeed.

brandAmbeed
catalog numberA309111-10g
cas100286-90-6
size10g

Available pack sizes

brand size price
Ambeed 10g 12218.50 Pln
Ambeed 50mg 259.12 Pln
Ambeed 100mg 381.50 Pln
Ambeed 250mg 637.38 Pln
Ambeed 1g 2239.38 Pln
Ambeed 5g 7657.25 Pln

properties

purity98%
delivery time 1-2 weeks
ambeed catalog no.A309111
Structural formula: {0} (CAS {1})

Irinotecan hydrochloride (anhydrous) is a hydrochloride obtained by combining irinotecan with one molar equivalent of hydrochloric acid. Used (in the form of its trihydrate) in combination with fluorouracil and leucovorin, for the treatment of patients with metastatic adenocarcinoma of the pancreas after disease progression following gemcitabine-based therapy. It is converted via hydrolysis of the carbamate linkage to its active metabolite, SN-38, which is ~1000 times more active. It has a role as an antineoplastic agent, a prodrug, an EC 5.99.1.2 (DNA topoisomerase) inhibitor and an apoptosis inducer. It contains an irinotecan(1+).

Source: ChEBI

Identity
Molecular formulaC33H39ClN4O6
Molecular weight623.1 g/mol
IUPAC name[(19S)-10,19-diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl] 4-piperidin-1-ylpiperidine-1-carboxylate;hydrochloride
InChIKeyGURKHSYORGJETM-WAQYZQTGSA-N
SMILESCCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)O)C2=NC5=C1C=C(C=C5)OC(=O)N6CCC(CC6)N7CCCCC7.Cl

Computed by PubChem (NCBI)

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