JTE-607, 98%

cas: 188791-09-5 — see every product listed under this CAS number, including other names

JTE-607, 98% (CAS 188791-09-5) is a chemical reagent available from Chemat. Available pack sizes: 50mg, 250mg. Offered by: Ambeed.

brandAmbeed
catalog numberA1493432-50mg
cas188791-09-5
size50mg
Need more information?

Ask us about this product — we're happy to help.

Available pack sizes

brand size price
Ambeed 50mg 1210.31 Pln
Ambeed 250mg 3162.75 Pln

properties

purity98%
delivery time 2-3 weeks
Structural formula: {0} (CAS {1})

JTE-607 dihydrochloride is the dihydrochloride salt of JTE-607. It is a cytokine inhibitor which suppresses the production of proinflammatory cytokines such as interleukin (IL-1beta), IL-6, IL-8, granulocyte macrophage colony stimulating factor (GM-CSF), and tumor necrosis factor (TNF-alpha). It acts as a pro-drug which is cleaved by carboxylesterase 1 (CES1) to its active free acid form, which then binds to cleavage and polyadenylation specificity factor 3 (CPSF3). It has a role as a CPSF3 inhibitor, an antineoplastic agent, a prodrug, an anti-inflammatory agent, an apoptosis inducer and a cardioprotective agent. It contains a JTE-607(2+).

Source: ChEBI

Identity
Molecular formulaC25H33Cl4N3O5
Molecular weight597.4 g/mol
IUPAC nameethyl (2S)-2-[[3,5-dichloro-2-hydroxy-4-[2-(4-methylpiperazin-1-yl)ethoxy]benzoyl]amino]-3-phenylpropanoate;dihydrochloride
InChIKeyJUJAUEQJEWIWCQ-FJSYBICCSA-N
SMILESCCOC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C2=CC(=C(C(=C2O)Cl)OCCN3CCN(CC3)C)Cl.Cl.Cl

Computed by PubChem (NCBI)

Synonyms: C25H33Cl4N3O5, orb1305042

Also listed as

JTE 607 dihydrochloride GLPBio CAS 188791-09-5
JTE-607/ 98.72% (existing batch purity) TargetMol CAS 188791-09-5
Jte 607 dihydrochloride Biosynth CAS 188791-09-5
(S)-Ethyl 2-(3,5-dichloro-2-hydroxy-4-(2-(4-methylpiperazin-1-yl)ethoxy)benzamido)-3-phenylpropanoate dihydrochloride, 98%, 98% Chemat CAS 188791-09-5
JTE-607, 99.27% MedChemExpress CAS 188791-09-5