JTE 607 dihydrochloride

cas: 188791-09-5 — see every product listed under this CAS number, including other names

JTE 607 dihydrochloride (CAS 188791-09-5) is a chemical reagent available from Chemat. Available pack sizes: 5mg, 1mg, 10mg, 25mg, 10mM (in 1ml dmso), 50mg, 100mg. Offered by: GLPBio, Biosynth.

brandGLPBio
catalog numberGC50117-5
cas188791-09-5
size5mg
Need more information?

Ask us about this product — we're happy to help.

Available pack sizes

brand size price
GLPBio 5mg 817.02 Pln
GLPBio 1mg 606.40 Pln
GLPBio 10mg 1055.73 Pln
GLPBio 25mg 1678.24 Pln
GLPBio 10mM (in 1ml dmso) 938.72 Pln
GLPBio 50mg 2310.10 Pln
Biosynth 50mg price on request
Biosynth 25mg price on request
Biosynth 100mg price on request

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

JTE-607 dihydrochloride is the dihydrochloride salt of JTE-607. It is a cytokine inhibitor which suppresses the production of proinflammatory cytokines such as interleukin (IL-1beta), IL-6, IL-8, granulocyte macrophage colony stimulating factor (GM-CSF), and tumor necrosis factor (TNF-alpha). It acts as a pro-drug which is cleaved by carboxylesterase 1 (CES1) to its active free acid form, which then binds to cleavage and polyadenylation specificity factor 3 (CPSF3). It has a role as a CPSF3 inhibitor, an antineoplastic agent, a prodrug, an anti-inflammatory agent, an apoptosis inducer and a cardioprotective agent. It contains a JTE-607(2+).

Source: ChEBI

Identity
Molecular formulaC25H33Cl4N3O5
Molecular weight597.4 g/mol
IUPAC nameethyl (2S)-2-[[3,5-dichloro-2-hydroxy-4-[2-(4-methylpiperazin-1-yl)ethoxy]benzoyl]amino]-3-phenylpropanoate;dihydrochloride
InChIKeyJUJAUEQJEWIWCQ-FJSYBICCSA-N
SMILESCCOC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C2=CC(=C(C(=C2O)Cl)OCCN3CCN(CC3)C)Cl.Cl.Cl

Computed by PubChem (NCBI)

Synonyms: C25H33Cl4N3O5, orb1305042

Also listed as

JTE-607/ 98.72% (existing batch purity) TargetMol CAS 188791-09-5
Jte 607 dihydrochloride Biosynth CAS 188791-09-5
JTE-607 98% Ambeed CAS 188791-09-5
(S)-Ethyl 2-(3,5-dichloro-2-hydroxy-4-(2-(4-methylpiperazin-1-yl)ethoxy)benzamido)-3-phenylpropanoate dihydrochloride, 98%, 98% Chemat CAS 188791-09-5
JTE-607, 99.27% MedChemExpress CAS 188791-09-5