JTE-607, 99.27%
cas: 188791-09-5 — see every product listed under this CAS number, including other names
JTE-607, 99.27% (CAS 188791-09-5) is a chemical reagent available from Chemat. Available pack sizes: 10 mg, 5 mg, 50 mg, 10mM/1mL, 25 mg, 100 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-110133-10 mg |
| cas | 188791-09-5 |
| size | 10 mg |
| availability | In stock |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 10 mg | 1072.02 Pln | |
| MedChemExpress | 5 mg | 649.42 Pln | |
| MedChemExpress | 50 mg | 3287.21 Pln | |
| MedChemExpress | 10mM/1mL | 816.60 Pln | |
| MedChemExpress | 25 mg | 2126.21 Pln | |
| MedChemExpress | 100 mg | 4773.29 Pln |
properties
| delivery time | 1-2 weeks |
|---|---|
| purity | 99.27% |
JTE-607 dihydrochloride is the dihydrochloride salt of JTE-607. It is a cytokine inhibitor which suppresses the production of proinflammatory cytokines such as interleukin (IL-1beta), IL-6, IL-8, granulocyte macrophage colony stimulating factor (GM-CSF), and tumor necrosis factor (TNF-alpha). It acts as a pro-drug which is cleaved by carboxylesterase 1 (CES1) to its active free acid form, which then binds to cleavage and polyadenylation specificity factor 3 (CPSF3). It has a role as a CPSF3 inhibitor, an antineoplastic agent, a prodrug, an anti-inflammatory agent, an apoptosis inducer and a cardioprotective agent. It contains a JTE-607(2+).
Source: ChEBI
| Molecular formula | C25H33Cl4N3O5 |
|---|---|
| Molecular weight | 597.4 g/mol |
| IUPAC name | ethyl (2S)-2-[[3,5-dichloro-2-hydroxy-4-[2-(4-methylpiperazin-1-yl)ethoxy]benzoyl]amino]-3-phenylpropanoate;dihydrochloride |
| InChIKey | JUJAUEQJEWIWCQ-FJSYBICCSA-N |
| SMILES | CCOC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C2=CC(=C(C(=C2O)Cl)OCCN3CCN(CC3)C)Cl.Cl.Cl |
Computed by PubChem (NCBI)
Synonyms:
C25H33Cl4N3O5, orb1305042