L-Norleucine, L-leucyl-6-diazo-5-oxo-, ethyl ester, 98+%, 98+%
cas: 1998725-11-3 — see every product listed under this CAS number, including other names
L-Norleucine, L-leucyl-6-diazo-5-oxo-, ethyl ester, 98+%, 98+% (CAS 1998725-11-3) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 5mg, 10mg, 25mg, 50mg. Offered by: Chemat.
| brand | Chemat |
|---|---|
| catalog number | Ch12MVLC-1mg |
| cas | 1998725-11-3 |
| size | 1mg |
| availability | 0.1g |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Chemat | 1mg | 539.60 Pln | |
| Chemat | 5mg | 1274.00 Pln | |
| Chemat | 10mg | 2003.60 Pln | |
| Chemat | 25mg | 3746.00 Pln | |
| Chemat | 50mg | 6323.60 Pln |
properties
| purity | 98+% |
|---|---|
| delivery time | 3 weeks |
JHU083 is an ethyl ester resulting from the formal condensation of the carboxy group of L-leucyl-6-diazo-5-oxo-L-norleucine with ethanol. It is a glutaminase inhibitor and a prodrug of 6-diazo-5-oxo-L-norleucine that exhibits antineoplastic activity. It has a role as an antineoplastic agent, a prodrug and an EC 3.5.1.2 (glutaminase) inhibitor. It is a secondary carboxamide, a ketone, an ethyl ester, a L-leucine derivative and a diazo compound.
Source: ChEBI
| Molecular formula | C14H24N4O4 |
|---|---|
| Molecular weight | 312.36 g/mol |
| IUPAC name | ethyl (2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-6-diazo-5-oxohexanoate |
| InChIKey | YZRCHOFKIPHQBW-RYUDHWBXSA-N |
| SMILES | CCOC(=O)[C@H](CCC(=O)C=[N+]=[N-])NC(=O)[C@H](CC(C)C)N |
Computed by PubChem (NCBI)
Synonyms:
ethyl (2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-6-diazo-5-oxohexanoate, ethyl (2S)-2-(((2S)-2-amino-4-methylpentanoyl)amino)-6-diazo-5-oxohexanoate, ethyl (2S)-2-{[(2S)-2-amino-4-methylpentanoyl]amino}-6-diazo-5-oxohexanoate, L-Norleucine, L-leucyl-6-diazo-5-oxo-, ethyl ester, orb1707162, orb3054177, ethyl (S)-2-((S)-2-amino-4-methylpentanamido)-6-diazo-5-oxohexanoate, ethyl L-leucyl-6-diazo-5-oxo-L-norleucinate