LCL161, 99.91%
cas: 1005342-46-0 — see every product listed under this CAS number, including other names
LCL161, 99.91% (CAS 1005342-46-0) is a chemical reagent available from Chemat. Available pack sizes: 50 mg, 10mM/1mL, 5 mg, 10 mg, 100 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-15518-50 mg |
| cas | 1005342-46-0 |
| size | 50 mg |
| availability | In stock |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 50 mg | 1847.57 Pln | |
| MedChemExpress | 10mM/1mL | 751.58 Pln | |
| MedChemExpress | 5 mg | 695.86 Pln | |
| MedChemExpress | 10 mg | 867.68 Pln | |
| MedChemExpress | 100 mg | 2883.18 Pln |
properties
| delivery time | 1-2 weeks |
|---|---|
| purity | 99.91% |
LCL161 is a small molecule inhibitor of IAPs that has potent antitumour activity in a range of solid tumours. In HCC, response to LCL161 therapy has shown to be mediated by Bcl-2 expression. It has a role as an antineoplastic agent and an apoptosis inducer. It is a member of 1,3-thiazoles, a N-acylpyrrolidine, an aromatic ketone, a member of monofluorobenzenes and a L-alanine derivative.
Source: ChEBI
| Molecular formula | C26H33FN4O3S |
|---|---|
| Molecular weight | 500.6 g/mol |
| IUPAC name | (2S)-N-[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(4-fluorobenzoyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxoethyl]-2-(methylamino)propanamide |
| InChIKey | UFPFGVNKHCLJJO-SSKFGXFMSA-N |
| SMILES | C[C@@H](C(=O)N[C@@H](C1CCCCC1)C(=O)N2CCC[C@H]2C3=NC(=CS3)C(=O)C4=CC=C(C=C4)F)NC |
Computed by PubChem (NCBI)