LDN-212854, 99.62%
cas: 1432597-26-6 — see every product listed under this CAS number, including other names
LDN-212854, 99.62% (CAS 1432597-26-6) is a chemical reagent available from Chemat. Available pack sizes: 100 mg, 1 g, 10 mg, 10mM/1mL, 5 mg, 25 mg, 50 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-15897-100 mg |
| cas | 1432597-26-6 |
| size | 100 mg |
| availability | In stock |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 100 mg | 4364.62 Pln | |
| MedChemExpress | 1 g | 14033.42 Pln | |
| MedChemExpress | 10 mg | 1202.05 Pln | |
| MedChemExpress | 10mM/1mL | 760.87 Pln | |
| MedChemExpress | 5 mg | 705.14 Pln | |
| MedChemExpress | 25 mg | 2014.75 Pln | |
| MedChemExpress | 50 mg | 2952.84 Pln |
properties
| delivery time | 1-2 weeks |
|---|---|
| purity | 99.62% |
LDN-212854 is a member of the class of quinolines that is quinoline substituted by a 6-[4-(piperazin-1-yl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl group at position 5. It is a potent ALK inhibitor (IC50 values of 2.4, 1.3, 85.8, 2,133 and 9,276 nM for ALK1, ALK2, ALK3, ALK4 and ALK5, respectively). It has a role as an EC 2.7.11.30 (receptor protein serine/threonine kinase) inhibitor, an antineoplastic agent and an angiogenesis inhibitor. It is a member of quinolines, a pyrazolopyrimidine and a N-arylpiperazine.
Source: ChEBI
| Molecular formula | C25H22N6 |
|---|---|
| Molecular weight | 406.5 g/mol |
| IUPAC name | 5-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline |
| InChIKey | BBDGBGOVJPEFBT-UHFFFAOYSA-N |
| SMILES | C1CN(CCN1)C2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=C6C=CC=NC6=CC=C5)N=C3 |
Computed by PubChem (NCBI)
Synonyms:
5-(6-(4-(piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline, 5-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline, 5-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline, 5-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline, orb1226289, orb1307185, s7147, 5-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-alpha]pyrimidin-3-yl]quinoline, quinoline, 5-[6-[4-(1-piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-