LY-411575, >95.0%(HPLC)(qNMR)
cas: 209984-57-6 — see every product listed under this CAS number, including other names
LY-411575, >95.0%(HPLC)(qNMR) (CAS 209984-57-6) is a chemical reagent available from Chemat. Available pack sizes: 5mg. Offered by: TCI.
| brand | TCI |
|---|---|
| catalog number | L0359-5MG |
| cas | 209984-57-6 |
| size | 5mg |
| availability | 2 tygodnie|2 weeks |
Documents:
Safety Data Sheet (MSDS)
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| TCI | 5mg | 360.78 Pln |
properties
| delivery time | 2 weeks |
|---|---|
| category | chemicals |
| purity | >95.0%(HPLC)(qNMR) |
LY-411575 is a dibenzoazepine that is 5,7-dihydro-6H-dibenzo[b,d]azepin-6-one which is substituted at the 7 pro-S position by the C-terminal carboxamide nitrogen of N2-[(2S)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]-L-alaninamide. It is a potent, cell permeable and selective gamma-secretase inhibitor. It has been tested as a possible treatment for Alzheimer's disease and shows promise for its potential to counteract severe hearing loss. It has a role as an EC 3.4.23.46 (memapsin 2) inhibitor. It is a lactam, a secondary alcohol, a difluorobenzene and a dibenzoazepine.
Source: ChEBI
| Molecular formula | C26H23F2N3O4 |
|---|---|
| Molecular weight | 479.5 g/mol |
| IUPAC name | (2S)-2-[[(2S)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]amino]-N-[(7S)-5-methyl-6-oxo-7H-benzo[d][1]benzazepin-7-yl]propanamide |
| InChIKey | ULSSJYNJIZWPSB-CVRXJBIPSA-N |
| SMILES | C[C@@H](C(=O)N[C@H]1C2=CC=CC=C2C3=CC=CC=C3N(C1=O)C)NC(=O)[C@H](C4=CC(=CC(=C4)F)F)O |
Computed by PubChem (NCBI)
Synonyms:
orb1225693, orb1301106