LY-411575, 98.68%

cas: 209984-57-6 — see every product listed under this CAS number, including other names

LY-411575, 98.68% (CAS 209984-57-6) is a chemical reagent available from Chemat. Available pack sizes: 25 mg, 1 g, 10 mg, 50 mg, 10mM/1mL, 100 mg, 5 mg. Offered by: MedChemExpress.

brandMedChemExpress
catalog numberHY-50752-25 mg
cas209984-57-6
size25 mg
availability In stock
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Available pack sizes

brand size price
MedChemExpress 25 mg 1559.64 Pln
MedChemExpress 1 g 14033.42 Pln
MedChemExpress 10 mg 751.58 Pln
MedChemExpress 50 mg 2650.98 Pln
MedChemExpress 10mM/1mL 528.67 Pln
MedChemExpress 100 mg 4025.60 Pln
MedChemExpress 5 mg 491.52 Pln

properties

delivery time 1-2 weeks
purity98.68%
Structural formula: {0} (CAS {1})

LY-411575 is a dibenzoazepine that is 5,7-dihydro-6H-dibenzo[b,d]azepin-6-one which is substituted at the 7 pro-S position by the C-terminal carboxamide nitrogen of N2-[(2S)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]-L-alaninamide. It is a potent, cell permeable and selective gamma-secretase inhibitor. It has been tested as a possible treatment for Alzheimer's disease and shows promise for its potential to counteract severe hearing loss. It has a role as an EC 3.4.23.46 (memapsin 2) inhibitor. It is a lactam, a secondary alcohol, a difluorobenzene and a dibenzoazepine.

Source: ChEBI

Identity
Molecular formulaC26H23F2N3O4
Molecular weight479.5 g/mol
IUPAC name(2S)-2-[[(2S)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]amino]-N-[(7S)-5-methyl-6-oxo-7H-benzo[d][1]benzazepin-7-yl]propanamide
InChIKeyULSSJYNJIZWPSB-CVRXJBIPSA-N
SMILESC[C@@H](C(=O)N[C@H]1C2=CC=CC=C2C3=CC=CC=C3N(C1=O)C)NC(=O)[C@H](C4=CC(=CC(=C4)F)F)O

Computed by PubChem (NCBI)

Synonyms: orb1225693, orb1301106

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