cas: 700874-72-2 — see every product listed under this CAS number, including other names
LY2157299, >95% (HPLC) (CAS 700874-72-2) is a chemical reagent available from Chemat. Available pack sizes: 25mg, 5mg. Offered by: TRC.
| brand | TRC |
|---|---|
| catalog number | TRC-L486320-25MG |
| cas | 700874-72-2 |
| size | 25mg |
Ask us about this product — we're happy to help.
| brand | size | price | |
|---|---|---|---|
| TRC | 25mg | price on request | |
| TRC | 5mg | price on request |
| purity | >95% (HPLC) |
|---|---|
| delivery time | To be confirmed by Chemat |
LY-2157299 is a pyrrolopyrazole that is 5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole which is substituted at positions 2 and 3 by 6-methylpyridin-2-yl and 6-(aminocarbonyl)quinolin-4-yl groups, respectively. A Transforming growth factor-betaRI (TGF-betaRI) kinase inhibitor, it blocks TGF-beta-mediated tumor growth in glioblastoma. It has a role as an antineoplastic agent and a TGFbeta receptor antagonist. It is a member of methylpyridines, a member of quinolines, a monocarboxylic acid amide, a pyrrolopyrazole and an aromatic amide.
Source: ChEBI
| Molecular formula | C22H19N5O |
|---|---|
| Molecular weight | 369.4 g/mol |
| IUPAC name | 4-[2-(6-methyl-2-pyridinyl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]quinoline-6-carboxamide |
| InChIKey | IVRXNBXKWIJUQB-UHFFFAOYSA-N |
| SMILES | CC1=NC(=CC=C1)C2=NN3CCCC3=C2C4=C5C=C(C=CC5=NC=C4)C(=O)N |
Computed by PubChem (NCBI)