LY3009120 99%
cas: 1454682-72-4 — see every product listed under this CAS number, including other names
LY3009120 99% (CAS 1454682-72-4) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 2mg, 5mg, 10mg, 25mg, 50mg, 100mg, 250mg. Offered by: Ambeed.
| brand | Ambeed |
|---|---|
| catalog number | A417155-1mg |
| cas | 1454682-72-4 |
| size | 1mg |
Documents:
Safety Data Sheet (MSDS)
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Ambeed | 1mg | 181.25 Pln | |
| Ambeed | 2mg | 209.06 Pln | |
| Ambeed | 5mg | 281.38 Pln | |
| Ambeed | 10mg | 453.81 Pln | |
| Ambeed | 25mg | 954.44 Pln | |
| Ambeed | 50mg | 1583.00 Pln | |
| Ambeed | 100mg | 2651.00 Pln | |
| Ambeed | 250mg | 4458.81 Pln | |
| Ambeed | 1g | 11907.00 Pln |
properties
| purity | 99% |
|---|---|
| delivery time | 2-3 weeks |
| ambeed catalog no. | A417155 |
LY3009120 is a member of the class of pyridopyrimidines that is pyrido[2,3-d]pyrimidine substituted by methylamino, 5-{[(3,3-dimethylbutyl)carbamoyl]amino}-4-fluoro-2-methylphenyl, and methyl groups at positions 2, 6 and 7, respectively. It is a potent pan RAF inhibitor which inhibits BRAFV600E, BRAFWT and CRAFWT (IC50 = 5.8, 9.1 and 15 nM, respectively). It also inhibits RAF homo- and heterodimers and exhibits anti-cancer properties. It has a role as an autophagy inducer, a necroptosis inhibitor, an antineoplastic agent, an apoptosis inducer and a B-Raf inhibitor. It is a member of phenylureas, an aminotoluene, an aromatic amine, a pyridopyrimidine, a secondary amino compound, a biaryl and a member of monofluorobenzenes.
Source: ChEBI
| Molecular formula | C23H29FN6O |
|---|---|
| Molecular weight | 424.5 g/mol |
| IUPAC name | 1-(3,3-dimethylbutyl)-3-[2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl]phenyl]urea |
| InChIKey | HHCBMISMPSAZBF-UHFFFAOYSA-N |
| SMILES | CC1=CC(=C(C=C1C2=C(N=C3C(=C2)C=NC(=N3)NC)C)NC(=O)NCCC(C)(C)C)F |
Computed by PubChem (NCBI)