LY3039478

cas: 1421438-81-4 — see every product listed under this CAS number, including other names

LY3039478 (CAS 1421438-81-4) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 100mg, 2mg, 25mg, 5mg, 10mM (in 1ml dmso), 50mg. Offered by: GLPBio.

brandGLPBio
catalog numberGC12653-10
cas1421438-81-4
size10mg
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Available pack sizes

brand size price
GLPBio 10mg 1256.99 Pln
GLPBio 100mg 4734.60 Pln
GLPBio 2mg 756.18 Pln
GLPBio 25mg 2099.48 Pln
GLPBio 5mg 943.40 Pln
GLPBio 10mM (in 1ml dmso) 952.76 Pln
GLPBio 50mg 3110.47 Pln

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Crenigacestat (LY3039478) is an orally active Notch and g-secretase inhibitor, with an IC50 of 1 nM in most of the tumor cell lines tested.

Source: ChEBI

Identity
Molecular formulaC22H23F3N4O4
Molecular weight464.4 g/mol
IUPAC name4,4,4-trifluoro-N-[(2S)-1-[[(7S)-5-(2-hydroxyethyl)-6-oxo-7H-pyrido[2,3-d][3]benzazepin-7-yl]amino]-1-oxopropan-2-yl]butanamide
InChIKeyYCBAQKQAINQRFW-UGSOOPFHSA-N
SMILESC[C@@H](C(=O)N[C@H]1C2=CC=CC=C2C3=C(N=CC=C3)N(C1=O)CCO)NC(=O)CCC(F)(F)F

Computed by PubChem (NCBI)

Synonyms: Crenigacestat, crenigacestatum, Gamma-Secretase Inhibitor LY3039478, Crenigacestat [USAN], Crenigacestat (LY3039478), CRENIGACESTAT [INN], Crenigacestat (USAN/INN), CRENIGACESTAT [WHO-DD], orb1226314, orb1303976

Also listed as

LY 3039478 TRC CAS 1421438-81-4
Crenigacestat/ 98.76% (existing batch purity) TargetMol CAS 1421438-81-4
Crenigacestat 95% Ambeed CAS 1421438-81-4
N-[(1S)-2-[[(7S)-6,7-Dihydro-5-(2-hydroxyethyl)-6-oxo-5H-pyrido[3,2-a][3]benzazepin-7-yl]amino]-1-methyl-2-oxoethyl]-4,4,4-trifluorobutanamide, 95%, 95% Chemat CAS 1421438-81-4
Crenigacestat, 99.01% MedChemExpress CAS 1421438-81-4