Products 1424635-83-5
CAS 1424635-83-5 appears in our catalog under these names: Lats–IN–1, Lats-IN-1/ 97.54% (existing batch purity), Lats-in-1, TRULI 98%, TRULI, 98%, 98%. Offered by: GLPBio, TargetMol, Biosynth, Ambeed, Chemat. Available pack sizes: 5mg, 10mg, 25mg, 1mg, 50mg, 100mg, 200mg, 250mg.
TRULI is a pyrrolopyridine that is 1H-pyrrolo[2,3-b]pyridine substituted by a N-(3-benzyl-1,3-thiazol-2(3H)-ylidene)carboxamide group at position 3. It is a potent and ATP-competitive inhibitor of LATS1 and LATS2 kinases, and a YAP signaling activator. It has a role as an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor. It is a member of benzenes, a member of 1,3-thiazoles, a pyrrolopyridine and an enamide.
Source: ChEBI
| Molecular formula | C18H14N4OS |
|---|---|
| Molecular weight | 334.4 g/mol |
| IUPAC name | N-(3-benzyl-1,3-thiazol-2-ylidene)-1H-pyrrolo[2,3-b]pyridine-3-carboxamide |
| InChIKey | VTXBMVZVPUSAJF-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C=C1)CN2C=CSC2=NC(=O)C3=CNC4=C3C=CC=N4 |
Computed by PubChem (NCBI)