Linagliptin - Bio-X â„¢

cas: 668270-12-0 — see every product listed under this CAS number, including other names

Linagliptin - Bio-X â„¢ (CAS 668270-12-0) is a chemical reagent available from Chemat. Available pack sizes: 25mg. Offered by: Biosynth.

brandBiosynth
catalog numberBL164627-25mg
cas668270-12-0
size25mg
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Available pack sizes

brand size price
Biosynth 25mg price on request

properties

categoryLife Sciences
sub-category 1Ligands
sub-category 2Enzyme Modulators
purityNo data
delivery time1-2 weeks
Structural formula: {0} (CAS {1})

Linagliptin is a xanthine that is 7H-xanthine bearing (4-methylquinazolin-2-yl)methyl, methyl, but-2-yn-1-yl and 3-aminopiperidin-1-yl substituents at positions 1, 3, 7 and 8 respectively (the R-enantiomer). Used for treatment of type II diabetes. It has a role as a hypoglycemic agent and an EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor. It is a member of quinazolines and an aminopiperidine. It is functionally related to a 7H-xanthine.

Source: ChEBI

Identity
Molecular formulaC25H28N8O2
Molecular weight472.5 g/mol
IUPAC name8-[(3R)-3-aminopiperidin-1-yl]-7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]purine-2,6-dione
InChIKeyLTXREWYXXSTFRX-QGZVFWFLSA-N
SMILESCC#CCN1C2=C(N=C1N3CCC[C@H](C3)N)N(C(=O)N(C2=O)CC4=NC5=CC=CC=C5C(=N4)C)C

Computed by PubChem (NCBI)

Synonyms: Linagliptin, Tradjenta, Trazenta, Trajenta, linagliptine, Linagliptina, GLYXAMBI COMPONENT LINAGLIPTIN, TRIJARDY XR COMPONENT LINAGLIPTIN, linagliptinum, Ondero
Related forms of this compound
8-[(3R)-3-amino-2,2,6,6-tetradeuteriopiperidin-1-yl]-7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]purine-2,6-dione C25H28N8O2
8-[(3S)-3-aminopiperidin-1-yl]-7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]purine-2,6-dione C25H28N8O2
8-[(3R)-3-aminopiperidin-1-yl]-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-7-(4,4,4-trideuterio(413C)but-2-ynyl)purine-2,6-dione C25H28N8O2
8-(3-aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]purine-2,6-dione C25H28N8O2
8-[(3R)-3-aminopiperidin-1-yl]-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-7-(4,4,4-trideuteriobut-2-ynyl)purine-2,6-dione C25H28N8O2
Isomers (same molecular formula)
7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-8-[[(3S)-piperidin-3-yl]amino]purine-2,6-dione C25H28N8O2
8-[(3R)-3-aminopiperidin-1-yl]-7-but-2-ynyl-3-methyl-2-[(4-methylquinazolin-2-yl)methoxy]purin-6-one C25H28N8O2
7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-8-[[(3R)-piperidin-3-yl]amino]purine-2,6-dione C25H28N8O2
8-[(3R)-3-aminopiperidin-1-yl]-7-buta-1,2-dienyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]purine-2,6-dione C25H28N8O2
8-[(3R)-3-aminopiperidin-1-yl]-7-but-2-ynyl-3-methyl-6-[(4-methylquinazolin-2-yl)methoxy]purin-2-one C25H28N8O2

Also listed as

Linagliptin Chemat Brand CAS 668270-12-0
Linagliptin, >95% (HPLC) TRC CAS 668270-12-0
Linagliptin/ 99.95% (existing batch purity) TargetMol CAS 668270-12-0
Linagliptin (BI–1356) GLPBio CAS 668270-12-0
Linagliptin, >98.0%(HPLC)(T) TCI CAS 668270-12-0
Linagliptin, 98.00% Chemat CAS 668270-12-0
(R)-8-[3-Aminopiperidin-1-yl]-7-(2-butynyl)-3-methyl-1-(4-methylquinazolin-2-ylmethyl)xanthine, 98%, 98% Chemat CAS 668270-12-0
Linagliptin, 99.91% MedChemExpress CAS 668270-12-0
Linagliptin (Standard) MedChemExpress CAS 668270-12-0
Linagliptin, 99% Ambeed CAS 668270-12-0