Products 668270-12-0

CAS 668270-12-0 appears in our catalog under these names: Linagliptin, Linagliptin, >95% (HPLC), Linagliptin/ 99.95% (existing batch purity), Linagliptin (BI–1356), Linagliptin - Bio-X â„¢. Offered by: Chemat Brand, TRC, Mikromol, LoGiCal, TargetMol. Available pack sizes: on request, 100mg, 10mg, 500mg, 250mg, 50mg, 1g, 10mM (in 1ml dmso).

Linagliptin
Chemat Brand, Mikromol, LoGiCal
  • size: on request, 250mg, 10mg, 0,5g
  • Variants: 8
from 776.58
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Linagliptin, >95% (HPLC)
TRC
  • size: 100mg, 10mg, 500mg
  • Variants: 3
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Linagliptin/ 99.95% (existing batch purity)
TargetMol
  • size: 50mg, 100mg
  • Variants: 2
from 439.25
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Linagliptin (BI–1356)
GLPBio
  • size: 100mg, 1g, 10mM (in 1ml dmso), 500mg
  • Variants: 4
from 573.64
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Linagliptin - Bio-X â„¢
Biosynth
  • size: 25mg
  • Variants: 1
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Linagliptin, >98.0%(HPLC)(T)
TCI
  • size: 1g
  • Variants: 1
from 542.72
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Linagliptin, 98.00%
Chemat
  • size: 1g, 250mg, 50mg
  • Variants: 3
from 236.55
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Linagliptin 99%
Ambeed
  • size: 250mg, 1g, 5g, 10g
  • Variants: 5
from 186.81
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(R)-8-[3-Aminopiperidin-1-yl]-7-(2-butynyl)-3-methyl-1-(4-methylquinazolin-2-ylmethyl)xanthine, 98%, 98%
Chemat
  • size: 250mg, 1g, 5g, 10g
  • Variants: 5
from 102.80
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Linagliptin, 99.91%
MedChemExpress
  • size: 100 mg, 500 mg, 1 g, 10mM/1mL
  • Variants: 4
from 412.57
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Linagliptin (Standard)
MedChemExpress
  • size: 25 mg, 100 mg, 50 mg, 10 mg
  • Variants: 5
from 245.39
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Structural formula: {0} (CAS {1})

Linagliptin is a xanthine that is 7H-xanthine bearing (4-methylquinazolin-2-yl)methyl, methyl, but-2-yn-1-yl and 3-aminopiperidin-1-yl substituents at positions 1, 3, 7 and 8 respectively (the R-enantiomer). Used for treatment of type II diabetes. It has a role as a hypoglycemic agent and an EC 3.4.14.5 (dipeptidyl-peptidase IV) inhibitor. It is a member of quinazolines and an aminopiperidine. It is functionally related to a 7H-xanthine.

Source: ChEBI

Identity
Molecular formulaC25H28N8O2
Molecular weight472.5 g/mol
IUPAC name8-[(3R)-3-aminopiperidin-1-yl]-7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]purine-2,6-dione
InChIKeyLTXREWYXXSTFRX-QGZVFWFLSA-N
SMILESCC#CCN1C2=C(N=C1N3CCC[C@H](C3)N)N(C(=O)N(C2=O)CC4=NC5=CC=CC=C5C(=N4)C)C

Computed by PubChem (NCBI)

Synonyms: Linagliptin, Tradjenta, Trazenta, Trajenta, linagliptine, Linagliptina, GLYXAMBI COMPONENT LINAGLIPTIN, TRIJARDY XR COMPONENT LINAGLIPTIN, linagliptinum, Ondero
Related forms of this compound
8-[(3R)-3-amino-2,2,6,6-tetradeuteriopiperidin-1-yl]-7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]purine-2,6-dione C25H28N8O2
8-[(3S)-3-aminopiperidin-1-yl]-7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]purine-2,6-dione C25H28N8O2
8-[(3R)-3-aminopiperidin-1-yl]-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-7-(4,4,4-trideuterio(413C)but-2-ynyl)purine-2,6-dione C25H28N8O2
8-(3-aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]purine-2,6-dione C25H28N8O2
8-[(3R)-3-aminopiperidin-1-yl]-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-7-(4,4,4-trideuteriobut-2-ynyl)purine-2,6-dione C25H28N8O2
Isomers (same molecular formula)
7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-8-[[(3S)-piperidin-3-yl]amino]purine-2,6-dione C25H28N8O2
8-[(3R)-3-aminopiperidin-1-yl]-7-but-2-ynyl-3-methyl-2-[(4-methylquinazolin-2-yl)methoxy]purin-6-one C25H28N8O2
7-but-2-ynyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]-8-[[(3R)-piperidin-3-yl]amino]purine-2,6-dione C25H28N8O2
8-[(3R)-3-aminopiperidin-1-yl]-7-buta-1,2-dienyl-3-methyl-1-[(4-methylquinazolin-2-yl)methyl]purine-2,6-dione C25H28N8O2
8-[(3R)-3-aminopiperidin-1-yl]-7-but-2-ynyl-3-methyl-6-[(4-methylquinazolin-2-yl)methoxy]purin-2-one C25H28N8O2