Linsitinib, 98%
cas: 867160-71-2 — see every product listed under this CAS number, including other names
Linsitinib, 98% (CAS 867160-71-2) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 2mg, 5mg, 10mg, 50mg, 100mg, 250mg. Offered by: Fluorochem.
| brand | Fluorochem |
|---|---|
| catalog number | F884006-1MG |
| cas | 867160-71-2 |
| size | 1mg |
| availability | In Stock China |
Documents:
Safety Data Sheet (MSDS)
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Fluorochem | 1mg | 227.02 Pln | |
| Fluorochem | 2mg | 294.71 Pln | |
| Fluorochem | 5mg | 424.87 Pln | |
| Fluorochem | 10mg | 700.81 Pln | |
| Fluorochem | 50mg | 1835.83 Pln | |
| Fluorochem | 100mg | 2538.71 Pln | |
| Fluorochem | 250mg | 3736.20 Pln |
properties
| purity | 98% |
|---|---|
| dual use | No |
| currency | EUR |
| delivery time | 3-4 weeks |
| category | Odczynniki chemiczne |
Linsitinib is an imidazopyrazine that is imidazo[1,5-a]pyrazine substituted by 2-phenylquinolin-7-yl, cis-3-hydroxy-3-methylcyclobutyl, and amino groups at positions 1, 3, and 8, respectively. It is dual inhibitor of the IGF-1 receptor and insulin receptor (IC50 = 35 and 75 nM, respectively) that was previously in clinical development for the treatment of cancer and thyroid eye disease. It has a role as an antineoplastic agent, an antimycobacterial drug, an apoptosis inducer and an insulin-like growth factor receptor 1 antagonist. It is a member of cyclobutanes, a member of benzenes, a member of quinolines, a tertiary alcohol, an aromatic amine and an imidazopyrazine.
Source: ChEBI
| Molecular formula | C26H23N5O |
|---|---|
| Molecular weight | 421.5 g/mol |
| IUPAC name | 3-[8-amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutan-1-ol |
| InChIKey | PKCDDUHJAFVJJB-UHFFFAOYSA-N |
| SMILES | CC1(CC(C1)C2=NC(=C3N2C=CN=C3N)C4=CC5=C(C=C4)C=CC(=N5)C6=CC=CC=C6)O |
Computed by PubChem (NCBI)