Lotilaner, 99%

cas: 1369852-71-0 — see every product listed under this CAS number, including other names

Lotilaner, 99% (CAS 1369852-71-0) is a chemical reagent available from Chemat. Available pack sizes: 5mg, 1mg. Offered by: AmBeed.

brandAmBeed
catalog numberA1142906-5mg
cas1369852-71-0
size5mg
availability USA Stock: 2.3g
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Available pack sizes

brand size price
AmBeed 5mg 205.41 Pln
AmBeed 1mg 174.16 Pln

properties

purity99%
delivery time1-2 weeks (only if in stock, to check click on availability)
Structural formula: {0} (CAS {1})

Lotilaner is a member of the class of isoxazoles that is 4,5-dihydro-1,2-oxazole substituted by 4-methyl-5-({2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl}carbamoyl)thiophen-2-yl, trifluoromethyl, and 3,4,5-trichlorophenyl groups at positions 3, 5 and 5, respectively (the 5S-stereoisomer). It is a gamma-aminobutyric acid (GABA)-gated chloride channel inhibitor selective for mites, approved for the treatment of Demodex blepharitis. It has a role as an ectoparasiticide, a GABA-gated chloride channel antagonist and an ophthalmology drug. It is a secondary carboxamide, a member of thiophenes, a trichlorobenzene, an organofluorine compound and a member of isoxazoles.

Source: ChEBI

Identity
Molecular formulaC20H14Cl3F6N3O3S
Molecular weight596.8 g/mol
IUPAC name3-methyl-N-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]-5-[(5S)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]thiophene-2-carboxamide
InChIKeyHDKWFBCPLKNOCK-SFHVURJKSA-N
SMILESCC1=C(SC(=C1)C2=NO[C@@](C2)(C3=CC(=C(C(=C3)Cl)Cl)Cl)C(F)(F)F)C(=O)NCC(=O)NCC(F)(F)F

Computed by PubChem (NCBI)

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