Lotilaner

cas: 1369852-71-0 — see every product listed under this CAS number, including other names

Lotilaner (CAS 1369852-71-0) is a chemical reagent available from Chemat. Available pack sizes: 50mg, 10mg, 1mg, 10mM (in 1ml dmso), 25mg, 5mg, 2mg, 1x10mg. Offered by: TRC, Dr. Ehrenstorfer, GLPBio, Biosynth.

brandTRC
catalog numberTRC-L470620-50MG
cas1369852-71-0
size50mg
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Available pack sizes

brand size price
TRC 50mg price on request
Dr. Ehrenstorfer 10mg price on request
GLPBio 1mg 793.62 Pln
GLPBio 10mg 1954.38 Pln
GLPBio 10mM (in 1ml dmso) 1664.19 Pln
GLPBio 25mg 3952.96 Pln
GLPBio 5mg 1364.64 Pln
GLPBio 50mg 4673.76 Pln
Biosynth 1mg price on request
Biosynth 2mg price on request
Biosynth 5mg price on request
Biosynth 25mg price on request
Biosynth 10mg price on request
HPC Standards 1x10mg 942.01 Pln

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Lotilaner is a member of the class of isoxazoles that is 4,5-dihydro-1,2-oxazole substituted by 4-methyl-5-({2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl}carbamoyl)thiophen-2-yl, trifluoromethyl, and 3,4,5-trichlorophenyl groups at positions 3, 5 and 5, respectively (the 5S-stereoisomer). It is a gamma-aminobutyric acid (GABA)-gated chloride channel inhibitor selective for mites, approved for the treatment of Demodex blepharitis. It has a role as an ectoparasiticide, a GABA-gated chloride channel antagonist and an ophthalmology drug. It is a secondary carboxamide, a member of thiophenes, a trichlorobenzene, an organofluorine compound and a member of isoxazoles.

Source: ChEBI

Identity
Molecular formulaC20H14Cl3F6N3O3S
Molecular weight596.8 g/mol
IUPAC name3-methyl-N-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]-5-[(5S)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]thiophene-2-carboxamide
InChIKeyHDKWFBCPLKNOCK-SFHVURJKSA-N
SMILESCC1=C(SC(=C1)C2=NO[C@@](C2)(C3=CC(=C(C(=C3)Cl)Cl)Cl)C(F)(F)F)C(=O)NCC(=O)NCC(F)(F)F

Computed by PubChem (NCBI)

Synonyms: Lotilaner, Credelio, XDEMVY, lotilanerum, Lotilaner (ema epar: veterinary), Credelio CAT, Lotilaner ophthalmic solution, Lotilaner [INN], Lotilaner [USAN:INN], Xdemvy (TN)

Also listed as

Lotilaner, 99% AmBeed CAS 1369852-71-0
Lotilaner/ 99.32% (existing batch purity) TargetMol CAS 1369852-71-0
Lotilaner 99% Ambeed CAS 1369852-71-0
Lotilaner, 99.84% MedChemExpress CAS 1369852-71-0