Lotilaner, 99.84%
cas: 1369852-71-0 — see every product listed under this CAS number, including other names
Lotilaner, 99.84% (CAS 1369852-71-0) is a chemical reagent available from Chemat. Available pack sizes: 100 mg, 50 mg, 25 mg, 10mM/1mL, 10 mg, 5 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-116564-100 mg |
| cas | 1369852-71-0 |
| size | 100 mg |
| availability | In stock |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 100 mg | 5493.11 Pln | |
| MedChemExpress | 50 mg | 3477.61 Pln | |
| MedChemExpress | 25 mg | 2172.65 Pln | |
| MedChemExpress | 10mM/1mL | 788.74 Pln | |
| MedChemExpress | 10 mg | 983.78 Pln | |
| MedChemExpress | 5 mg | 630.84 Pln |
properties
| delivery time | 1-2 weeks |
|---|---|
| purity | 99.84% |
Lotilaner is a member of the class of isoxazoles that is 4,5-dihydro-1,2-oxazole substituted by 4-methyl-5-({2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl}carbamoyl)thiophen-2-yl, trifluoromethyl, and 3,4,5-trichlorophenyl groups at positions 3, 5 and 5, respectively (the 5S-stereoisomer). It is a gamma-aminobutyric acid (GABA)-gated chloride channel inhibitor selective for mites, approved for the treatment of Demodex blepharitis. It has a role as an ectoparasiticide, a GABA-gated chloride channel antagonist and an ophthalmology drug. It is a secondary carboxamide, a member of thiophenes, a trichlorobenzene, an organofluorine compound and a member of isoxazoles.
Source: ChEBI
| Molecular formula | C20H14Cl3F6N3O3S |
|---|---|
| Molecular weight | 596.8 g/mol |
| IUPAC name | 3-methyl-N-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]-5-[(5S)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]thiophene-2-carboxamide |
| InChIKey | HDKWFBCPLKNOCK-SFHVURJKSA-N |
| SMILES | CC1=C(SC(=C1)C2=NO[C@@](C2)(C3=CC(=C(C(=C3)Cl)Cl)Cl)C(F)(F)F)C(=O)NCC(=O)NCC(F)(F)F |
Computed by PubChem (NCBI)