Products 251456-60-7
CAS 251456-60-7 appears in our catalog under these names: 4-(Dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide, >97.0%(HPLC), 4-(Dimethylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide, 97%, 97%, N-Hydroxy-7-(4-dimethylaminobenzoyl)aminoheptanamide, M344, 98+%, M344/ 99.95% (existing batch purity). Offered by: TCI, Chemat, TRC, AmBeed, TargetMol. Available pack sizes: 20mg, 100mg, 25mg, 50mg, 250mg, 1g, 5mg, 1mg.
4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide is a benzamide resulting from the formal condensation of the carboxy group of 4-(dimethylamino)benzoic acid with the amino group of 7-amino-N-hydroxyheptanamide. It is a potent inhibitor of histone deacetylases and induces cell cycle arrest and apoptosis in several human cancer cell lines. It has a role as an antineoplastic agent, an EC 3.5.1.98 (histone deacetylase) inhibitor and an apoptosis inducer. It is a secondary carboxamide, a member of benzamides, a hydroxamic acid and a tertiary amino compound.
Source: ChEBI
| Molecular formula | C16H25N3O3 |
|---|---|
| Molecular weight | 307.39 g/mol |
| IUPAC name | 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide |
| InChIKey | MXWDSZWTBOCWBK-UHFFFAOYSA-N |
| SMILES | CN(C)C1=CC=C(C=C1)C(=O)NCCCCCCC(=O)NO |
Computed by PubChem (NCBI)
Synonyms:
4-(dimethylamino)-n-[7-(hydroxyamino)-7-oxoheptyl]benzamide, 4-(dimethylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide, Histone Deacetylase Inhibitor III, N-Hydroxy-7-(4-dimethylaminobenzoyl)aminoheptanamide, 4-Dimethylamino-N-(6-hydroxycarbamoylhexyl)benzamide, 7-((4-(dimethylamino)phenyl)formamido)-N-hydroxyheptanamide, 4-(dimethylamino)-NHAOBzNH2, m344, Benzamide, 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]-, Benzamide, 4-(dimethylamino)-N-(7-(hydroxyamino)-7-oxoheptyl)-