MK 1775

cas: 955365-80-7 — see every product listed under this CAS number, including other names

MK 1775 (CAS 955365-80-7) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 50mg. Offered by: Biosynth.

brandBiosynth
catalog numberBM161385-10mg
cas955365-80-7
size10mg
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Available pack sizes

brand size price
Biosynth 10mg price on request
Biosynth 50mg price on request

properties

categoryLife Sciences
sub-category 1Ligands
sub-category 2Enzyme Modulators
purityNo data
delivery time1-2 weeks

Adavosertib is a member of the class of pyrazolopyrimidines that is 1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one substituted by 6-(2-hydroxypropan-2-yl)pyridin-2-yl, prop-1-en-3-yl, [4-(4-methylpiperazin-1-yl)phenyl]amino groups at positions 1, 2, and 6, respectively. It is a potent and selective oral inhibitor of WEE1 kinase. It has a role as an antineoplastic agent and an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor. It is a member of pyridines, a tertiary alcohol, a pyrazolopyrimidine, a N-arylpiperazine, a N-methylpiperazine and a secondary amino compound.

Source: ChEBI

Identity
Molecular formulaC27H32N8O2
Molecular weight500.6 g/mol
IUPAC name1-[6-(2-hydroxypropan-2-yl)-2-pyridinyl]-6-[4-(4-methylpiperazin-1-yl)anilino]-2-prop-2-enylpyrazolo[3,4-d]pyrimidin-3-one
InChIKeyBKWJAKQVGHWELA-UHFFFAOYSA-N
SMILESCC(C)(C1=NC(=CC=C1)N2C3=NC(=NC=C3C(=O)N2CC=C)NC4=CC=C(C=C4)N5CCN(CC5)C)O

Computed by PubChem (NCBI)

Synonyms: Adavosertib, adavosertibum, Adavosertib (MK-1775), Adavosertib (USAN), ADAVOSERTIB [USAN], Adavosertib; MK-1775; MK 1775, Adavosertib (Standard), Kinome_2656, ADAVOSERTIB [INN], Adavosertib; MK-1775
Isomers (same molecular formula)
4-[[6-[4-[(3R)-3-[(2,5,7-trimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)oxy]pyrrolidin-1-yl]phenyl]pyridazin-3-yl]methyl]morpholine C27H32N8O2
N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[[4-(8-methylimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide C27H32N8O2

Also listed as

Adavosertib (MK-1775) Chemat Brand CAS 955365-80-7
MK 1775, >95% (HPLC) TRC CAS 955365-80-7
Adavosertib/ 99.53% (existing batch purity) TargetMol CAS 955365-80-7
MK–1775 GLPBio CAS 955365-80-7
2-Allyl-1-[6-(1-hydroxy-1-methylethyl)pyridin-2-yl]-6-[[4-(4-methylpiperazin-1-yl)phenyl]amino]-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one, 98%, 98% Chemat CAS 955365-80-7
Adavosertib, 99.96% MedChemExpress CAS 955365-80-7
Adavosertib (Standard), 99.93% MedChemExpress CAS 955365-80-7
MK 1775, min. 95 %, 10 mg Roth CAS 955365-80-7
MK 1775, min. 95 %, 50 mg Roth CAS 955365-80-7
2-Allyl-1-[6-(1-hydroxy-1-methylethyl)pyridin-2-yl]-6-[[4-(4-methylpiperazin-1-yl)phenyl]amino]-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one, 98% Fluorochem CAS 955365-80-7