MK–1775

cas: 955365-80-7 — see every product listed under this CAS number, including other names

MK–1775 (CAS 955365-80-7) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 100mg, 5mg, 10mM (in 1ml dmso), 50mg. Offered by: GLPBio.

brandGLPBio
catalog numberGC16030-10
cas955365-80-7
size10mg
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Available pack sizes

brand size price
GLPBio 10mg 859.15 Pln
GLPBio 100mg 2544.13 Pln
GLPBio 5mg 704.69 Pln
GLPBio 10mM (in 1ml dmso) 742.14 Pln
GLPBio 50mg 1739.08 Pln

properties

purityNo data
delivery timeTo be confirmed by Chemat

Adavosertib is a member of the class of pyrazolopyrimidines that is 1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one substituted by 6-(2-hydroxypropan-2-yl)pyridin-2-yl, prop-1-en-3-yl, [4-(4-methylpiperazin-1-yl)phenyl]amino groups at positions 1, 2, and 6, respectively. It is a potent and selective oral inhibitor of WEE1 kinase. It has a role as an antineoplastic agent and an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor. It is a member of pyridines, a tertiary alcohol, a pyrazolopyrimidine, a N-arylpiperazine, a N-methylpiperazine and a secondary amino compound.

Source: ChEBI

Identity
Molecular formulaC27H32N8O2
Molecular weight500.6 g/mol
IUPAC name1-[6-(2-hydroxypropan-2-yl)-2-pyridinyl]-6-[4-(4-methylpiperazin-1-yl)anilino]-2-prop-2-enylpyrazolo[3,4-d]pyrimidin-3-one
InChIKeyBKWJAKQVGHWELA-UHFFFAOYSA-N
SMILESCC(C)(C1=NC(=CC=C1)N2C3=NC(=NC=C3C(=O)N2CC=C)NC4=CC=C(C=C4)N5CCN(CC5)C)O

Computed by PubChem (NCBI)

Synonyms: Adavosertib, adavosertibum, Adavosertib (MK-1775), Adavosertib (USAN), ADAVOSERTIB [USAN], Adavosertib; MK-1775; MK 1775, Adavosertib (Standard), Kinome_2656, ADAVOSERTIB [INN], Adavosertib; MK-1775
Isomers (same molecular formula)
4-[[6-[4-[(3R)-3-[(2,5,7-trimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)oxy]pyrrolidin-1-yl]phenyl]pyridazin-3-yl]methyl]morpholine C27H32N8O2
N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[[4-(8-methylimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]amino]phenyl]prop-2-enamide C27H32N8O2

Also listed as

Adavosertib (MK-1775) Chemat Brand CAS 955365-80-7
MK 1775, >95% (HPLC) TRC CAS 955365-80-7
Adavosertib/ 99.53% (existing batch purity) TargetMol CAS 955365-80-7
MK 1775 Biosynth CAS 955365-80-7
2-Allyl-1-[6-(1-hydroxy-1-methylethyl)pyridin-2-yl]-6-[[4-(4-methylpiperazin-1-yl)phenyl]amino]-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one, 98%, 98% Chemat CAS 955365-80-7
Adavosertib, 99.96% MedChemExpress CAS 955365-80-7
Adavosertib (Standard), 99.93% MedChemExpress CAS 955365-80-7
MK 1775, min. 95 %, 10 mg Roth CAS 955365-80-7
MK 1775, min. 95 %, 50 mg Roth CAS 955365-80-7
2-Allyl-1-[6-(1-hydroxy-1-methylethyl)pyridin-2-yl]-6-[[4-(4-methylpiperazin-1-yl)phenyl]amino]-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-one, 98% Fluorochem CAS 955365-80-7