Methyl (1S,3R)-2-(2-chloroacetyl)-1-(4-methoxycarbonylphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-3-carboxylate, 98%, 98%

cas: 1219810-16-8 — see every product listed under this CAS number, including other names

Methyl (1S,3R)-2-(2-chloroacetyl)-1-(4-methoxycarbonylphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-3-carboxylate, 98%, 98% (CAS 1219810-16-8) is a chemical reagent available from Chemat. Available pack sizes: 5g, 10g, 10mg, 25mg, 50mg, 100mg, 250mg, 1g. Offered by: Chemat.

brandChemat
catalog numberCh110CNR-5g
cas1219810-16-8
size5g
availability 10g
Need more information?

Ask us about this product — we're happy to help.

Available pack sizes

brand size price
Chemat 5g 6107.60 Pln
Chemat 10g 11128.40 Pln
Chemat 10mg 150.80 Pln
Chemat 25mg 227.60 Pln
Chemat 50mg 338.00 Pln
Chemat 100mg 477.20 Pln
Chemat 250mg 890.00 Pln
Chemat 1g 2128.40 Pln

properties

purity98%
delivery time3 weeks
Structural formula: {0} (CAS {1})

RSL3 is a beta-carboline that is 2,3,4,4a,9,9a-hexahydro-1H-beta-carboline in which the hydrogens at positions 1, 2 and 3 are replaced by 4-(methoxycarbonyl)phenyl, chloroacetyl and methoxycarbonyl groups, respectively (the 1S,2R stereoisomer). It is a potential antineoplastic agent which triggers ferroptosis by inactivating the glutathione peroxidase 4 (GPX4) enzyme. It has a role as a ferroptosis inducer, an EC 1.11.1.9 (glutathione peroxidase) inhibitor and an antineoplastic agent. It is a tertiary carboxamide, a methyl ester, a benzoate ester, an organochlorine compound, a diester and a member of beta-carbolines.

Source: ChEBI

Identity
Molecular formulaC23H23ClN2O5
Molecular weight442.9 g/mol
IUPAC namemethyl (1S,3R)-2-(2-chloroacetyl)-1-(4-methoxycarbonylphenyl)-1,3,4,4a,9,9a-hexahydropyrido[3,4-b]indole-3-carboxylate
InChIKeyCKRZDIUOUCGSBK-YBKKDXPLSA-N
SMILESCOC(=O)[C@H]1CC2C([C@@H](N1C(=O)CCl)C3=CC=C(C=C3)C(=O)OC)NC4=CC=CC=C24

Computed by PubChem (NCBI)

Synonyms: ras-selective lethal small molecule 3
Isomers (same molecular formula)
1-(3-chlorobenzo[b][1]benzoxepin-5-yl)-4-methylpiperazin-4-ium;(Z)-4-hydroxy-4-oxobut-2-enoate C23H23ClN2O5
(3R,3aR,6R,6aR)-6-[[6-chloro-5-[4-[1-(hydroxymethyl)cyclopropyl]phenyl]-1H-benzimidazol-2-yl]oxy]-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-3-ol C23H23ClN2O5

Also listed as

RSL3/ 99.64% (existing batch purity) TargetMol CAS 1219810-16-8
RSL3 GLPBio CAS 1219810-16-8
RSL3, 99.87% MedChemExpress CAS 1219810-16-8
RSL3 (Standard) MedChemExpress CAS 1219810-16-8
RSL3 98% Ambeed CAS 1219810-16-8
RSL3, 98% Ambeed CAS 1219810-16-8