NF-╬║B Activation Inhibitor 1PC X 1MG

cas: 545380-34-5 — see every product listed under this CAS number, including other names

NF-╬║B Activation Inhibitor 1PC X 1MG (CAS 545380-34-5) is a chemical reagent available from Chemat. Available pack sizes: 1MG. Offered by: Sigma-Aldrich.

brandSigma-Aldrich
catalog number481406-1MG
cas545380-34-5
size1MG
availability availability
Documents: Safety Data Sheet (MSDS)
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Available pack sizes

brand size price
Sigma-Aldrich 1MG 616.00 Pln

properties

purityNo data
delivery time1-2 weeks (only if in stock, to check click on availability)
Structural formula: {0} (CAS {1})

EVP4593 is a member of the class of quinazolines that is quinazoline substituted by [2-(4-phenoxyphenyl)ethyl]amino and amino groups at positions 4 and 6, respectively. It is an inhibitor of NF-B signal transduction pathway and exhibits protective effects in oncology, cardiovascular disease and parasite invasion. It has a role as an antiparasitic agent, an antineoplastic agent, an EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitor, an anti-inflammatory agent, an apoptosis inducer and a NF-kappaB inhibitor. It is a member of benzenes, an aromatic ether, a member of quinazolines, a primary amino compound and a secondary amino compound.

Source: ChEBI

Identity
Molecular formulaC22H20N4O
Molecular weight356.4 g/mol
IUPAC name4-N-[2-(4-phenoxyphenyl)ethyl]quinazoline-4,6-diamine
InChIKeyIBAKVEUZKHOWNG-UHFFFAOYSA-N
SMILESC1=CC=C(C=C1)OC2=CC=C(C=C2)CCNC3=NC=NC4=C3C=C(C=C4)N

Computed by PubChem (NCBI)

Synonyms: QNZ quinazolinediamine, 6-Amino-4-(4-phenoxyphenylethylamino)quinazoline, QNZ, N4-(4-phenoxyphenethyl)quinazoline-4,6-diamine, 4-N-[2-(4-phenoxyphenyl)ethyl]quinazoline-4,6-diamine, NF-kB activation inhibitor, Curator_000005, N4-[2-(4-phenoxyphenyl)ethyl]quinazoline-4,6-diamine, 4,6-Quinazolinediamine, N4-[2-(4-phenoxyphenyl)ethyl]-, N~4~-[2-(4-Phenoxyphenyl)ethyl]quinazoline-4,6-diamine
Isomers (same molecular formula)
2-[4-(4-isoquinolin-4-ylphenyl)pyrazol-1-yl]-N,N-dimethylacetamide C22H20N4O
(E)-N-ethoxy-1-[1-(3-pyridin-3-ylphenyl)benzimidazol-5-yl]ethanimine C22H20N4O
4-[2-amino-5-(4-cyanophenyl)-3-pyridinyl]-N-propan-2-ylbenzamide C22H20N4O
(8-methyl-1,3,4,5-tetrahydropyrido[4,3-b]indol-2-yl)-(3-phenyl-1H-pyrazol-5-yl)methanone C22H20N4O

Also listed as

QNZ (EVP4593) GLPBio CAS 545380-34-5
6-Amino-4-(4-phenoxyphenylethylamino)quinazoline TRC CAS 545380-34-5
QNZ/ 99.86% (existing batch purity) TargetMol CAS 545380-34-5
QNZ, 98% Thermo Scientific (Alfa Aesar) CAS 545380-34-5
QNZ, >98.0%(HPLC) TCI CAS 545380-34-5
EVP4593 Biosynth CAS 545380-34-5
QNZ, 99.50% MedChemExpress CAS 545380-34-5
QNZ (Standard) MedChemExpress CAS 545380-34-5
N4-(4-Phenoxyphenethyl)quinazoline-4,6-diamine, 99% Fluorochem CAS 545380-34-5
QNZ, 99% Ambeed CAS 545380-34-5