Necrosulfonamide, >95.0%(HPLC)
cas: 1360614-48-7 — see every product listed under this CAS number, including other names
Necrosulfonamide, >95.0%(HPLC) (CAS 1360614-48-7) is a chemical reagent available from Chemat. Available pack sizes: 25mg. Offered by: TCI.
| brand | TCI |
|---|---|
| catalog number | N1201-25MG |
| cas | 1360614-48-7 |
| size | 25mg |
| availability | 2 tygodnie|2 weeks |
Documents:
Safety Data Sheet (MSDS)
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| TCI | 25mg | 501.89 Pln |
properties
| delivery time | 2 weeks |
|---|---|
| category | chemicals |
| purity | >95.0%(HPLC) |
Necrosulfonamide is a sulfonamide that is a 3-methoxypyrazin-2-yl derivative of (E)-N-(4-(N-(4,6-dimethylpyrimidin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophene-2-yl)acrylamide. Necrosulfonamide specifically blocks necrosis downstream of the activation of RIP3 (the receptor-interacting serine-threonine kinase 3), a key signalling molecule in the programmed necrosis (necroptosis) pathway. It has a role as a necroptosis inhibitor and a neuroprotective agent. It is a member of thiophenes, a sulfonamide and a member of pyrazines.
Source: ChEBI
| Molecular formula | C18H15N5O6S2 |
|---|---|
| Molecular weight | 461.5 g/mol |
| IUPAC name | (E)-N-[4-[(3-methoxypyrazin-2-yl)sulfamoyl]phenyl]-3-(5-nitrothiophen-2-yl)prop-2-enamide |
| InChIKey | FNPPHVLYVGMZMZ-XBXARRHUSA-N |
| SMILES | COC1=NC=CN=C1NS(=O)(=O)C2=CC=C(C=C2)NC(=O)/C=C/C3=CC=C(S3)[N+](=O)[O-] |
Computed by PubChem (NCBI)