Nelarabine

cas: 121032-29-9 — see every product listed under this CAS number, including other names

Nelarabine (CAS 121032-29-9) is a chemical reagent available from Chemat. Available pack sizes: on request, 100mg, 25mg, 5mg, 10mM (in 1ml dmso), 250mg, 500mg, 1000mg. Offered by: Chemat Brand, GLPBio, Biosynth.

brandChemat Brand
catalog numberULN521
cas121032-29-9
sizeon request
availability Do potwierdzenia przez Chemat|To be confirmed by Chemat
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Available pack sizes

brand size price
Chemat Brand on request price on request
GLPBio 100mg 3269.61 Pln
GLPBio 25mg 1355.28 Pln
GLPBio 5mg 685.97 Pln
GLPBio 10mM (in 1ml dmso) 737.45 Pln
Biosynth 250mg price on request
Biosynth 100mg price on request
Biosynth 500mg price on request
Biosynth 1000mg price on request
Biosynth 2000mg price on request

properties

purityNo data
categoryChemicals
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Nelarabine is a purine nucleoside in which O-methylguanine is attached to arabinofuranose via a beta-N9-glycosidic bond. Inhibits DNA synthesis and causes cell death; a prodrug of 9-beta-D-arabinofuranosylguanine (ara-G). It has a role as an antineoplastic agent, a prodrug and a DNA synthesis inhibitor. It is a purine nucleoside, a beta-D-arabinoside and a monosaccharide derivative. It is functionally related to a guanine and a 9-beta-D-arabinofuranosylguanine.

Source: ChEBI

Identity
Molecular formulaC11H15N5O5
Molecular weight297.27 g/mol
IUPAC name(2R,3S,4S,5R)-2-(2-amino-6-methoxypurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
InChIKeyIXOXBSCIXZEQEQ-UHTZMRCNSA-N
SMILESCOC1=NC(=NC2=C1N=CN2[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)O)N

Computed by PubChem (NCBI)

Synonyms: Nelarabine, Nelzarabine, Arranon, Atriance, Attriance, 2-Amino-6-methoxypurine arabinoside, compound 506U78, Nelarabina, 2-Amino-9-beta-D-arabinofuranosyl-6-methoxy-9H-purine, nelarabinum
Related forms of this compound
(2R,3R,4S,5R)-2-(2-amino-6-methoxypurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol C11H15N5O5
(2R,3R,4R,5R)-2-(2-amino-6-methoxypurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol C11H15N5O5
(2S,3S,4S,5R)-2-(2-amino-6-methoxypurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol C11H15N5O5
Isomers (same molecular formula)
2-amino-9-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-1H-purin-6-one C11H15N5O5
2-amino-9-[(2R,3R,4S,5R)-3-hydroxy-5-(hydroxymethyl)-4-methoxyoxolan-2-yl]-1H-purin-6-one C11H15N5O5
(2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-(hydroxymethylamino)purin-9-yl]oxolane-3,4-diol C11H15N5O5
2-amino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1-methylpurin-6-one C11H15N5O5
[2-[(2-amino-6-oxo-1H-purin-9-yl)methoxy]-3-hydroxypropyl] acetate C11H15N5O5
(2R,3S,4S,5R)-2-(2-amino-6-methoxypurin-7-yl)-5-(hydroxymethyl)oxolane-3,4-diol C11H15N5O5
2-amino-9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-1H-purin-6-one C11H15N5O5
(2R,3R,4S,5R)-2-(6-amino-2-methoxypurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol C11H15N5O5
N-[9-(1,3-dihydroxypropan-2-yloxymethyl)-6-oxo-1H-purin-2-yl]acetamide C11H15N5O5

Also listed as

Nelarabine, >95% (HPLC) TRC CAS 121032-29-9
Nelarabine/ 97.9% (existing batch purity) TargetMol CAS 121032-29-9
Nelarabine 98% Ambeed CAS 121032-29-9
9-β-D-Arabinofuranosyl-6-methoxy-9H-purin-2-amine, 98%, 98% Chemat CAS 121032-29-9
Nelarabine, 99.76% MedChemExpress CAS 121032-29-9
Nelarabine (Standard) MedChemExpress CAS 121032-29-9
Nelzarabine, 98% Fluorochem CAS 121032-29-9