Products 121032-29-9
CAS 121032-29-9 appears in our catalog under these names: Nelarabine, Nelarabine, >95% (HPLC), Nelarabine/ 97.9% (existing batch purity), Nelarabine 98%, 9-β-D-Arabinofuranosyl-6-methoxy-9H-purin-2-amine, 98%, 98%. Offered by: Chemat Brand, TRC, GLPBio, TargetMol, Biosynth. Available pack sizes: on request, 100mg, 10mg, 25mg, 5mg, 10mM (in 1ml dmso), 1mg, 2mg.
Nelarabine is a purine nucleoside in which O-methylguanine is attached to arabinofuranose via a beta-N9-glycosidic bond. Inhibits DNA synthesis and causes cell death; a prodrug of 9-beta-D-arabinofuranosylguanine (ara-G). It has a role as an antineoplastic agent, a prodrug and a DNA synthesis inhibitor. It is a purine nucleoside, a beta-D-arabinoside and a monosaccharide derivative. It is functionally related to a guanine and a 9-beta-D-arabinofuranosylguanine.
Source: ChEBI
| Molecular formula | C11H15N5O5 |
|---|---|
| Molecular weight | 297.27 g/mol |
| IUPAC name | (2R,3S,4S,5R)-2-(2-amino-6-methoxypurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol |
| InChIKey | IXOXBSCIXZEQEQ-UHTZMRCNSA-N |
| SMILES | COC1=NC(=NC2=C1N=CN2[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)O)N |
Computed by PubChem (NCBI)