Orteronel

cas: 566939-85-3 — see every product listed under this CAS number, including other names

Orteronel (CAS 566939-85-3) is a chemical reagent available from Chemat. Available pack sizes: 1g, 1mg, 10mg, 5mg, 50mg. Offered by: TRC, GLPBio.

brandTRC
catalog numberTRC-O697600-1G
cas566939-85-3
size1g
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Available pack sizes

brand size price
TRC 1g price on request
GLPBio 1mg 625.12 Pln
GLPBio 10mg 1294.43 Pln
GLPBio 5mg 901.27 Pln
GLPBio 50mg 2881.12 Pln

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Orteronel is a member of the class of pyrroloimidazoles that is 6,7-dihydro-5H-pyrrolo[1,2-c]imidazole substituted by hydroxy and 6-(methylcarbamoyl)naphthalen-2-yl groups at position 7 (the 7S-stereoisomer). It is a non-steroidal 17,20-lyase inhibitor that suppresses androgen synthesis. It was previously in clinical development for the treatment of castration-resistant prostate cancer trial now discontinued. It has a role as an antineoplastic agent, an EC 1.14.99.9 (steroid 17alpha-monooxygenase) inhibitor and a sterol biosynthesis inhibitor. It is a secondary carboxamide, a tertiary alcohol, a pyrroloimidazole and a naphthalenecarboxamide.

Source: ChEBI

Identity
Molecular formulaC18H17N3O2
Molecular weight307.3 g/mol
IUPAC name6-[(7S)-7-hydroxy-5,6-dihydropyrrolo[1,2-c]imidazol-7-yl]-N-methylnaphthalene-2-carboxamide
InChIKeyOZPFIJIOIVJZMN-SFHVURJKSA-N
SMILESCNC(=O)C1=CC2=C(C=C1)C=C(C=C2)[C@]3(CCN4C3=CN=C4)O

Computed by PubChem (NCBI)

Synonyms: Orteronel, orteronelum, Androgen Synthesis Inhibitor TAK-700, (S)-Orteronel, Orteronel [INN], Orteronel [USAN:INN], (+)-orteronel, 566939-85-3 (s-isomer), ORTERONEL [JAN], Orteronel (JAN/USAN)
Related forms of this compound
6-(7-hydroxy-5,6-dihydropyrrolo[1,2-c]imidazol-7-yl)-N-methylnaphthalene-2-carboxamide C18H17N3O2
Isomers (same molecular formula)
N-benzyl-2-(2,7-dimethylimidazo[1,2-a]pyridin-3-yl)-2-oxoacetamide C18H17N3O2
2-(4-ethoxyphenyl)quinoline-4-carbohydrazide C18H17N3O2
4-(1H-benzimidazol-2-yl)-1-(4-methoxyphenyl)pyrrolidin-2-one C18H17N3O2
4-(1H-benzimidazol-2-yl)-1-(2-methoxyphenyl)pyrrolidin-2-one C18H17N3O2
2-benzhydryl-2,5,7-triazaspiro[3.4]octane-6,8-dione C18H17N3O2
2-(3-ethoxyphenyl)quinoline-4-carbohydrazide C18H17N3O2
2-(6-methoxy-9,11,11-trimethyl-2-oxo-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-3-ylidene)propanedinitrile C18H17N3O2
ethyl 7-cyclopropyl-2-phenylpyrazolo[1,5-a]pyrimidine-6-carboxylate C18H17N3O2
4,5-dimethyl-2-(4-phenoxyanilino)-1H-pyrimidin-6-one C18H17N3O2
2-(2-ethoxyphenyl)quinoline-4-carbohydrazide C18H17N3O2
4-(1H-benzimidazol-2-yl)-1-(3-methoxyphenyl)pyrrolidin-2-one C18H17N3O2

Also listed as

CYP17A1 Inhibitor II, TAK-700 Biosynth CAS 566939-85-3
Orteronel 99% Ambeed CAS 566939-85-3
Orteronel, 99.70%, 99.70% Chemat CAS 566939-85-3
Orteronel, 99.90% MedChemExpress CAS 566939-85-3
CYP17A1 Inhibitor II, min. 95 %, TAK-700, 5 mg Roth CAS 566939-85-3
CYP17A1 Inhibitor II, min. 95 %, TAK-700, 10 mg Roth CAS 566939-85-3
CYP17A1 Inhibitor II, min. 95 %, TAK-700, 25 mg Roth CAS 566939-85-3
CYP17A1 Inhibitor II, min. 95 %, TAK-700, 50 mg Roth CAS 566939-85-3
CYP17A1 Inhibitor II, min. 95 %, TAK-700, 100 mg Roth CAS 566939-85-3