PF-00835231
cas: 870153-29-0 — see every product listed under this CAS number, including other names
PF-00835231 (CAS 870153-29-0) is a chemical reagent available from Chemat. Available pack sizes: 25MG, 5MG. Offered by: Sigma-Aldrich.
| brand | Sigma-Aldrich |
|---|---|
| catalog number | SML3314-25MG |
| cas | 870153-29-0 |
| size | 25MG |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Sigma-Aldrich | 25MG | 1290.00 Pln | |
| Sigma-Aldrich | 5MG | 361.00 Pln |
PF-00835231 is a primary alcohol resulting from the cleavage of the phosphate group of the prodrug PF-07304814. It is an inhibitor of SARS-CoV-1 and -2 main protease (3CLpro) and exhibits potent in vitro antiviral activity. It has a role as an EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor, an anticoronaviral agent and a drug metabolite. It is a secondary carboxamide, a primary alcohol, a L-leucine derivative, an aromatic ether, an indolecarboxamide and a member of pyrrolidin-2-ones.
Source: ChEBI
| Molecular formula | C24H32N4O6 |
|---|---|
| Molecular weight | 472.5 g/mol |
| IUPAC name | N-[(2S)-1-[[(2S)-4-hydroxy-3-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide |
| InChIKey | QDIMHKWNHMVDJB-WBAXXEDZSA-N |
| SMILES | CC(C)C[C@@H](C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)CO)NC(=O)C2=CC3=C(N2)C=CC=C3OC |
Computed by PubChem (NCBI)