Products 870153-29-0
CAS 870153-29-0 appears in our catalog under these names: PF–00835231, PF-00835231/ 99.3% (existing batch purity), PF 00835231, PF-00835231 95%, N-((S)-1-(((S)-4-Hydroxy-3-oxo-1-((S)-2-oxopyrrolidin-3-yl)butan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)-4-methoxy-1H-indole-2-carboxamide, 95%, 95%. Offered by: GLPBio, TargetMol, Biosynth, Ambeed, Chemat. Available pack sizes: 1mg, 10mg, 5mg, 10mM (in 1ml dmso), 50mg, 2mg, 25mg, 100mg.
PF-00835231 is a primary alcohol resulting from the cleavage of the phosphate group of the prodrug PF-07304814. It is an inhibitor of SARS-CoV-1 and -2 main protease (3CLpro) and exhibits potent in vitro antiviral activity. It has a role as an EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor, an anticoronaviral agent and a drug metabolite. It is a secondary carboxamide, a primary alcohol, a L-leucine derivative, an aromatic ether, an indolecarboxamide and a member of pyrrolidin-2-ones.
Source: ChEBI
| Molecular formula | C24H32N4O6 |
|---|---|
| Molecular weight | 472.5 g/mol |
| IUPAC name | N-[(2S)-1-[[(2S)-4-hydroxy-3-oxo-1-[(3S)-2-oxopyrrolidin-3-yl]butan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-methoxy-1H-indole-2-carboxamide |
| InChIKey | QDIMHKWNHMVDJB-WBAXXEDZSA-N |
| SMILES | CC(C)C[C@@H](C(=O)N[C@@H](C[C@@H]1CCNC1=O)C(=O)CO)NC(=O)C2=CC3=C(N2)C=CC=C3OC |
Computed by PubChem (NCBI)