PFI 3
cas: 1819363-80-8 — see every product listed under this CAS number, including other names
PFI 3 (CAS 1819363-80-8) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 5mg, 10mM (in 1ml dmso), 50mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC14361-10 |
| cas | 1819363-80-8 |
| size | 10mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 10mg | 985.52 Pln | |
| GLPBio | 5mg | 732.77 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 760.86 Pln | |
| GLPBio | 50mg | 2099.48 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
PFI-3 is an azabicycloalkane that is (1R,4R)-2,5-diazabicyclo[2.2.1]heptane which is substituted at position 2 by a 3-(2-hydroxyphenyl)-3-oxoprop-1-en-1-yl group and at position 5 by a pyridin-2-yl group. It is a potent and selective inhibitor of polybromo 1 (Kd = 48 nM), SMARCA2 and SMARCA4 (Kd = 89 nM) bromodomains. It is a member of pyridines, a member of phenols, an azabicycloalkane and an enone.
Source: ChEBI
| Molecular formula | C19H19N3O2 |
|---|---|
| Molecular weight | 321.4 g/mol |
| IUPAC name | (E)-1-(2-hydroxyphenyl)-3-[(1R,4R)-5-pyridin-2-yl-2,5-diazabicyclo[2.2.1]heptan-2-yl]prop-2-en-1-one |
| InChIKey | INAICWLVUAKEPB-QSTFCLMHSA-N |
| SMILES | C1[C@@H]2CN([C@H]1CN2C3=CC=CC=N3)/C=C/C(=O)C4=CC=CC=C4O |
Computed by PubChem (NCBI)